The following program presents principles 00:00:01.98\00:00:02.95 designed to promote good health 00:00:02.96\00:00:04.41 and is not intended to take the place of 00:00:04.42\00:00:06.32 personalized professional care. 00:00:06.33\00:00:08.30 The opinions and ideas expressed are 00:00:08.31\00:00:10.96 those of the speaker. Viewers are encouraged 00:00:10.97\00:00:13.38 to draw their own conclusions about 00:00:13.39\00:00:15.05 the information presented. 00:00:15.06\00:00:16.64 Hello and welcome to "Wonderfully Made" 00:00:37.11\00:00:39.48 this program is designed to provide information 00:00:40.09\00:00:43.09 and encouragement and promoting 00:00:43.10\00:00:45.57 good health habits. My name is Don Morgan 00:00:45.58\00:00:49.43 and I teach in the department of Heath 00:00:49.44\00:00:51.33 and Human Performance at Middle Tennessee 00:00:51.34\00:00:53.84 State University. This is the seventh 00:00:53.85\00:00:57.15 in a series of programs focusing on the health 00:00:57.16\00:01:00.25 benefits that come from begin physically 00:01:00.26\00:01:02.75 active on a daily basis. In today's program 00:01:02.76\00:01:06.39 we are going to be talking about the 00:01:06.40\00:01:08.64 growing epidemic of diabetes in the 00:01:08.65\00:01:11.63 United States, and the positive role that 00:01:11.64\00:01:14.96 physical activity and exercise can play 00:01:14.97\00:01:17.69 and helping to treat and manage this disease. 00:01:18.26\00:01:21.45 Let's first define what is meant by the term 00:01:22.22\00:01:25.59 diabetes. Diabetes is a group of diseases 00:01:25.60\00:01:30.48 that are characterized by high levels of sugar 00:01:30.49\00:01:33.63 or glucose in the blood. Glucose is used by 00:01:33.64\00:01:38.72 the body to provide energy to power many 00:01:38.73\00:01:41.52 body functions. People with diabetes have 00:01:41.53\00:01:45.33 increased levels of blood glucose 00:01:45.34\00:01:47.38 because of a lack of insulin or resistance 00:01:47.39\00:01:51.61 to insulin effects. Now what is insulin? 00:01:51.62\00:01:56.34 Well, it's simply a hormone release by the 00:01:57.45\00:02:00.84 pancreas gland that helps glucose to enter 00:02:00.85\00:02:04.30 into many body tissues, hence when there are 00:02:04.31\00:02:08.47 defects in either insulin production 00:02:08.48\00:02:11.00 or insulin action glucose can build up 00:02:11.01\00:02:15.18 in the blood and spill into the urine, 00:02:15.19\00:02:17.88 as a result the body can lose a main 00:02:18.65\00:02:22.28 source of fuel. How many people in the 00:02:22.29\00:02:26.78 United States have diabetes? 00:02:26.79\00:02:29.37 According to the Center for Disease Control, 00:02:30.99\00:02:33.05 nearly 21 million people or 7 percent 00:02:33.06\00:02:37.40 of the US population have diabetes, 00:02:37.41\00:02:40.47 defined as a fasting blood glucose levels 00:02:41.22\00:02:44.15 of at least a 126 mg/dl, over 14 million people 00:02:44.16\00:02:51.59 have been diagnosed with diabetes 00:02:51.60\00:02:53.52 while more than 6 million have the disease 00:02:54.35\00:02:56.70 but have not yet been diagnosed. 00:02:56.71\00:02:59.21 Another 41 million Americans have a 00:03:00.18\00:03:03.32 condition called pre-diabetes in which 00:03:03.33\00:03:07.22 blood glucose levels are higher than 00:03:07.23\00:03:09.61 normal but are not high enough to warrant a 00:03:09.62\00:03:13.24 diagnosing of diabetes. Based on information 00:03:13.25\00:03:17.98 from the National Institute of health, 00:03:17.99\00:03:19.87 having pre-diabetes can predisposed you 00:03:19.88\00:03:24.12 to a greater risk of developing diabetes 00:03:24.13\00:03:27.07 and the higher incidence of heart attack 00:03:27.08\00:03:29.86 and stroke. In 2005, 1 ½ million new cases of 00:03:29.87\00:03:36.62 diabetes were diagnosed in people aged 00:03:36.63\00:03:39.50 20 years and older, and by the year 2025, 00:03:39.51\00:03:44.19 it is estimated that diabetes will affect 00:03:44.20\00:03:47.42 nearly 9 percent of the US population. 00:03:47.43\00:03:51.57 The following graphic shows the spread of 00:03:52.49\00:03:55.42 diabetes in the United States over the 00:03:55.43\00:03:57.91 past decade. What is of interest to note is that 00:03:57.92\00:04:02.95 in 1994, only the Louisiana 00:04:02.96\00:04:06.41 and Mississippi pictured in dark blue 00:04:06.42\00:04:09.74 only these two states exhibited 00:04:09.75\00:04:13.08 an age-adjusted diabetes rate 00:04:13.09\00:04:14.98 of at least 6 percent. However, in 2004, 00:04:14.99\00:04:20.92 39 states were colored in dark blue, 00:04:20.93\00:04:24.25 reflecting a startling increase in the 00:04:24.26\00:04:28.03 National Insurance of Diabetes. 00:04:28.04\00:04:29.97 Over 200,000 people die each year from diabetes 00:04:29.98\00:04:35.35 related complications, and the overall risk 00:04:35.36\00:04:38.86 of death among people with diabetes is about 00:04:38.87\00:04:42.28 twice that a person of similar age 00:04:42.29\00:04:45.35 who do not have this disease. 00:04:45.36\00:04:47.18 From an economic prospective, 00:04:48.18\00:04:50.27 the estimated annual financial burden of 00:04:50.28\00:04:53.32 diabetes in the United States is 00:04:53.33\00:04:55.93 132 billion dollars while the prevalence 00:04:55.94\00:05:01.10 of diabetes is highest in adults who are 00:05:01.11\00:05:03.99 60 years and older. The greatest number of 00:05:04.00\00:05:07.67 new cases has been observed among 00:05:07.68\00:05:10.62 middle aged adults. It is also important 00:05:10.63\00:05:15.09 to note that diabetes is not just an 00:05:15.10\00:05:17.59 adult disease but is also being diagnosed 00:05:17.60\00:05:21.04 with greater frequency in children 00:05:21.05\00:05:23.47 and teenagers. As shown in the next graphic, 00:05:23.48\00:05:28.18 the Center for Disease Control estimated 00:05:28.19\00:05:31.49 that 1 out of 3 children born in the 00:05:31.50\00:05:34.44 United States in the year 2000 could develop 00:05:34.45\00:05:38.44 diabetes in their life time. 00:05:38.45\00:05:40.91 Diabetes can be classified is either 00:05:43.66\00:05:45.97 Type 1 or Type 2. In Type 1 diabetes, 00:05:45.98\00:05:51.65 little or no insulin is available as a result of 00:05:51.66\00:05:55.39 genetic or environmental factors that destroy 00:05:55.40\00:05:58.44 cells in the pancreas gland that is where 00:05:58.45\00:06:01.23 insulin is made. Hence persons with 00:06:01.24\00:06:05.65 Type 2 diabetes must take insulin daily 00:06:05.66\00:06:08.94 to function and live. Type 1 diabetes accounts 00:06:08.95\00:06:14.36 for about 5 to 10 percent of diagnosed 00:06:14.37\00:06:17.85 cases in the US and develops most often 00:06:17.86\00:06:21.40 in children and young adults. 00:06:21.41\00:06:22.92 The onset of Type 1 diabetes is usually 00:06:23.82\00:06:27.69 abrupt and it's generally accompanied 00:06:27.70\00:06:30.81 by frequent urination, constant hunger, 00:06:30.82\00:06:34.35 excessive thrust and unexplained weight loss. 00:06:35.24\00:06:38.98 Type 2 diabetes on the other hand is the 00:06:40.39\00:06:44.20 most common form of diabetes 00:06:44.21\00:06:46.20 and accounts for 90 to 95 percent of 00:06:46.21\00:06:49.55 diagnosed cases. This type of diabetes 00:06:49.56\00:06:53.87 can developed at any age even during childhood. 00:06:53.88\00:06:56.79 In this form of diabetes the pancreas usually 00:06:58.27\00:07:01.74 produces enough insulin but the body 00:07:01.75\00:07:04.79 can't use it effectively, 00:07:04.80\00:07:06.58 and develops what is known as 00:07:06.59\00:07:08.45 insulin resistance. To overcome 00:07:08.46\00:07:12.69 this resistance, the pancreas attempts 00:07:12.70\00:07:15.55 to make more insulin to facilitate 00:07:15.56\00:07:18.42 the entry of glucose into the body cells. 00:07:18.43\00:07:21.39 Unfortunately, overtime insulin production 00:07:22.32\00:07:27.28 may begin to diminish. The result is the 00:07:27.29\00:07:31.13 same as what happens for those individuals 00:07:31.14\00:07:33.27 with Type 1 diabetes, glucose levels 00:07:33.28\00:07:36.62 in the blood can increase to abnormally 00:07:36.63\00:07:39.37 high levels. Lifestyle factors can play 00:07:39.38\00:07:44.32 an important role in the development of diabetes. 00:07:44.33\00:07:47.99 In the United States approximately 00:07:48.94\00:07:52.02 85 percent of individuals with Type 2 00:07:52.03\00:07:54.99 diabetes are obese at the time of diagnosis. 00:07:55.00\00:07:58.75 This is led to the coining of the phrase 00:07:58.76\00:08:02.45 diabesity, to describe the close association 00:08:02.46\00:08:07.54 between Type 2 diabetes and elevated 00:08:07.55\00:08:11.27 levels of body fat. In a five years 00:08:11.28\00:08:15.06 study of 20,000 men, the risk of Type 2 00:08:15.07\00:08:19.34 diabetes was tripled at a body mass index 00:08:19.35\00:08:22.85 that exceeded overweight standards. 00:08:22.86\00:08:24.86 A similar trend linking increases in body 00:08:26.38\00:08:29.68 mass index to a greater age-adjusted risk in 00:08:29.69\00:08:32.78 Type 2 diabetes was also observed 00:08:32.79\00:08:35.99 then a group of 114,000 women who were 00:08:36.00\00:08:40.14 studied for 14 years. The risk of developing 00:08:40.15\00:08:44.71 Type 2 diabetes also arises with an increase 00:08:44.72\00:08:48.35 in waist circumference. In one study of 00:08:48.36\00:08:52.06 more than 43,000 women, it was found 00:08:52.07\00:08:55.66 that a 10 inch difference in waist 00:08:55.67\00:08:57.48 circumference in this case going from 00:08:57.49\00:08:59.86 a 28 inch weight size to a 38 inch 00:08:59.87\00:09:03.10 waist size that 10 inch difference translated 00:09:03.11\00:09:07.54 into a 6 fold increase in the risk of 00:09:07.55\00:09:10.47 developing Type 2 diabetes. 00:09:10.48\00:09:12.27 Other evidence indicates that when body weight 00:09:13.89\00:09:16.85 and abdominal fat are lost, 00:09:16.86\00:09:18.49 there is less resistance to the effects of 00:09:18.50\00:09:21.61 insulin and levels of blood glucose 00:09:21.62\00:09:24.50 or either reduced or return to normal. 00:09:24.51\00:09:27.94 What is the role of physical activity in 00:09:29.88\00:09:33.07 treating diabetes? In discussing this topic, 00:09:33.08\00:09:37.09 it's important to recognize that 00:09:37.10\00:09:39.66 physical activity has been used to treat 00:09:39.67\00:09:42.63 diabetes for 1000 of years. 00:09:42.64\00:09:44.94 Moreover, even after insulin was isolated in 00:09:46.03\00:09:50.11 1922, exercise was considered along 00:09:50.12\00:09:54.99 with diet and insulin as an important part 00:09:55.00\00:09:58.11 of the treatment regimen for diabetes. 00:09:58.12\00:10:00.57 Before we delve into exactly how 00:10:02.53\00:10:04.95 physical activity can impact the management of 00:10:04.96\00:10:08.38 diabetes, I want to look first at the overall 00:10:08.39\00:10:12.72 relationship between physical activity 00:10:12.73\00:10:14.99 and the risk of developing diabetes. 00:10:15.00\00:10:17.81 Data from a number of studies have provide 00:10:19.68\00:10:21.77 a convincing evidence for the role that 00:10:21.78\00:10:24.26 regular exercise can play in reducing 00:10:24.27\00:10:26.64 the risk of Type 2 diabetes. 00:10:26.65\00:10:28.49 In one study, the risk of Type 2 diabetes 00:10:29.23\00:10:33.37 increased as physical activity levels declined 00:10:33.38\00:10:37.35 and time spend watching TV increased. 00:10:37.36\00:10:40.74 In another study, it was demonstrated that person 00:10:42.28\00:10:45.69 with low levels of leisure time 00:10:45.70\00:10:47.42 physical activity were at the highest risk of 00:10:47.43\00:10:50.65 developing Type 2 diabetes. 00:10:50.66\00:10:52.81 While the lowest risk of Type 2 diabetes 00:10:54.26\00:10:57.03 was observed in the most active group. 00:10:57.04\00:10:59.14 Those individuals who displayed moderate 00:10:59.95\00:11:02.71 levels of physical activity demonstrated 00:11:02.72\00:11:05.61 marked reductions in disease risk compare 00:11:05.62\00:11:09.88 to the least active group. This finding is 00:11:09.89\00:11:13.80 consistent with what we have talked about 00:11:13.81\00:11:16.94 in earlier programs that is that numerous 00:11:16.95\00:11:21.08 health benefits can be gained by performing 00:11:21.09\00:11:23.87 moderate physical activity on a 00:11:23.88\00:11:26.65 regular basis. Exactly how does 00:11:26.66\00:11:32.01 physical activity aid in transporting blood sugar 00:11:32.02\00:11:36.00 into your muscles. When physical activity is 00:11:36.01\00:11:40.01 performed your muscles contract 00:11:40.02\00:11:42.96 and when they do, an insulin like 00:11:43.49\00:11:46.37 effect is created. What that means is that 00:11:46.38\00:11:50.52 when you are physical active glucose intake 00:11:50.53\00:11:53.58 into your muscles increases by 00:11:53.59\00:11:55.82 7 to 20 fold compared to resting conditions. 00:11:55.83\00:11:59.35 Within in the cell, muscle activity singles 00:12:00.24\00:12:03.86 what are known as glucose transporters 00:12:03.87\00:12:06.34 to migrate to the cell membrane 00:12:06.35\00:12:08.82 and usher glucose in. Since muscle activity 00:12:08.83\00:12:14.23 produces in insulin like effect, 00:12:14.24\00:12:16.53 less insulin is require to move glucose 00:12:17.42\00:12:20.02 into your muscles conversely during 00:12:20.03\00:12:24.20 and following exercise skeletal muscle 00:12:24.21\00:12:27.61 display an increase sensitivity to the 00:12:27.62\00:12:29.91 available insulin. What this means is that 00:12:29.92\00:12:34.16 for any given level of insulin? 00:12:34.17\00:12:35.87 More blood glucose can be moved into 00:12:36.84\00:12:38.91 the muscle and this effect can last anywhere 00:12:38.92\00:12:42.47 from several hours to a few days. 00:12:42.48\00:12:44.64 With training insulin sensitivity is elevated 00:12:46.05\00:12:50.23 due to an increase in the total content of 00:12:51.07\00:12:53.59 glucose transporters and the stronger insulin 00:12:53.60\00:12:56.95 effect at the cell level. This increase in 00:12:56.96\00:13:01.54 insulin sensitivity is what makes 00:13:01.55\00:13:04.21 physical activity so useful in treating 00:13:04.22\00:13:07.31 persons with diabetes, since it reduces 00:13:07.32\00:13:11.03 the need for insulin while helping to lower 00:13:11.04\00:13:14.33 blood glucose levels to more normal values. 00:13:14.34\00:13:17.59 Regular exercise and physical activity 00:13:19.92\00:13:22.85 can improve the health and quality of 00:13:22.86\00:13:24.63 life of both Type 1 and Type 2 diabetics. 00:13:24.64\00:13:28.78 Regular aerobic and resistance training 00:13:30.30\00:13:33.06 combine with dietary therapy can result in 00:13:33.37\00:13:37.44 better aerobic function, favorable changes 00:13:37.45\00:13:40.67 in cholesterol profiles, decreases in weight, 00:13:40.68\00:13:44.43 and blood pressure, and greater lean body mass. 00:13:44.44\00:13:48.58 In addition, daily physical activity 00:13:49.46\00:13:52.94 can help to improve the psychological 00:13:52.95\00:13:55.51 state of the diabetic by raising self esteem 00:13:55.52\00:13:59.00 and lowering depression and anxiety. 00:13:59.01\00:14:03.24 Regular physical activity can decrease 00:14:05.59\00:14:08.58 the insulin requirements of well controlled 00:14:08.59\00:14:12.09 Type 1 diabetics by 30 to 50 percent. 00:14:12.10\00:14:15.57 With each bout of exercise, 00:14:17.12\00:14:19.27 the improvement in insulin sensitivity 00:14:19.28\00:14:21.70 can last for 1 or 2 days before returning to 00:14:21.71\00:14:25.54 pre-exercise values. This finding highlights 00:14:25.55\00:14:30.35 the importance of being active on a daily basis, 00:14:30.36\00:14:33.71 so that you can take full advantage 00:14:34.54\00:14:36.48 of the enhancement in insulin sensitivity 00:14:36.49\00:14:39.33 that comes from engaging in single bouts 00:14:39.34\00:14:42.24 of physical activity and exercise. 00:14:42.25\00:14:45.12 Before starting an exercise program, 00:14:46.75\00:14:49.04 the Type 1 diabetic should undergo a 00:14:49.05\00:14:51.76 comprehensive medical screening, 00:14:51.77\00:14:53.51 since strenuous exercise can aggravate eye, 00:14:54.33\00:14:57.85 kidney or nerve problems that may already exist. 00:14:57.86\00:15:01.48 While the risk of hyperglycemia 00:15:03.19\00:15:05.33 or high blood sugar can be present in some 00:15:05.34\00:15:09.23 Type 1 diabetics who are not in good control of 00:15:09.24\00:15:11.90 their blood glucose levels. 00:15:11.91\00:15:13.44 The primary concern for these individuals 00:15:14.22\00:15:16.94 is to avoid hypoglycemia or low blood sugar 00:15:16.95\00:15:21.23 which may occur when exercise is prolong 00:15:21.95\00:15:24.84 or too intense or when blood glucose levels 00:15:24.85\00:15:28.38 are low prior to the start of exercise. 00:15:28.39\00:15:31.42 Given the insulin like effect created by muscle 00:15:32.84\00:15:36.23 contraction, individuals with Type 1 diabetes 00:15:36.24\00:15:39.91 who exercise regularly will require smaller 00:15:39.92\00:15:43.35 then normal insulin doses or will need to 00:15:43.36\00:15:46.40 increase food intake to maintain appropriate 00:15:46.41\00:15:49.80 levels of blood glucose. For the Type 1 diabetic, 00:15:49.81\00:15:54.26 exercise should be performed at the 00:15:55.12\00:15:57.05 same time everyday at about the 00:15:57.06\00:16:00.01 same intensity and for the same length of time. 00:16:00.02\00:16:03.60 The overall goal is to strive for regularity 00:16:05.08\00:16:08.76 and to avoid unplanned exercise 00:16:08.77\00:16:11.81 as much as possible. The most appropriate 00:16:11.82\00:16:15.69 exercises for Type 1 diabetics are those with 00:16:15.70\00:16:19.98 predictable levels of activity like walking 00:16:19.99\00:16:23.23 and cycling. They should also avoid heavy 00:16:23.24\00:16:27.36 resist of exercise or prolonged intense 00:16:27.37\00:16:30.81 aerobic activity that may exacerbate eye 00:16:30.82\00:16:34.24 and kidney problems due to marked increase 00:16:34.25\00:16:36.67 in blood pressure. It is strongly recommended 00:16:36.68\00:16:41.14 that Type 1 diabetics adopt a regular pattern 00:16:41.15\00:16:44.61 of exercise and diet with frequent 00:16:44.62\00:16:47.62 blood glucose measurements to test 00:16:47.63\00:16:50.05 the body's response to a given exercise load. 00:16:50.06\00:16:52.84 Each person with Type 1 diabetes is unique, 00:16:54.63\00:16:58.03 and will need to discover to frequent 00:16:58.88\00:17:01.87 and routine blood glucose monitoring. 00:17:01.88\00:17:04.50 The optimal schedule of diet, 00:17:05.33\00:17:07.27 physical activity, and insulin dosage 00:17:07.28\00:17:10.71 that produces a blood glucose range allowing 00:17:10.72\00:17:14.35 for safe exercise participation. 00:17:14.36\00:17:16.80 In summary, the individual with Type 1 00:17:18.28\00:17:22.14 diabetes has much to gain from engaging 00:17:22.15\00:17:25.41 in daily physical activity because of the 00:17:25.42\00:17:28.59 potential to enhance cardiovascular fitness, 00:17:28.60\00:17:31.16 control disease risk factors, 00:17:32.08\00:17:34.44 heighten psychological well being 00:17:34.45\00:17:37.24 and improve overall quality of life. 00:17:38.15\00:17:40.95 For the individual with Type 2 diabetes, 00:17:43.56\00:17:46.07 physical activity and exercise can enhance 00:17:46.96\00:17:50.13 long term diabetic control by reducing 00:17:50.14\00:17:54.08 insulin resistance and improving insulin 00:17:54.09\00:17:57.33 sensitivity. As with Type 1 diabetics, 00:17:57.34\00:18:01.28 persons with Type 2 diabetes should 00:18:01.29\00:18:04.66 undergo a thorough medical examination 00:18:04.67\00:18:07.07 to uncover previously undiagnosed medical 00:18:07.08\00:18:10.56 complications that may have risen as a result 00:18:10.57\00:18:14.45 of the disease. A number of risk factors are 00:18:14.46\00:18:19.07 associated with Type 2 diabetes. 00:18:19.08\00:18:21.10 As shown in the following graphic 00:18:21.89\00:18:24.11 they include age being 45 years or older, 00:18:24.12\00:18:28.83 having a body mass index of 25 kg/m2 00:18:28.84\00:18:33.62 or more which would suggest the presence of 00:18:33.63\00:18:36.62 overweightness or obesity, 00:18:36.63\00:18:38.47 having a parent, brother or sister with diabetes, 00:18:39.53\00:18:43.04 having a family background that is 00:18:43.05\00:18:46.14 African-American, American Indian, 00:18:46.15\00:18:48.86 Asian American, Pacific Islander, 00:18:48.87\00:18:51.76 or Hispanic American. Gestational diabetes 00:18:51.77\00:18:56.80 or giving birth to at least one baby 00:18:56.81\00:18:59.54 weighing nine pounds or more, 00:18:59.55\00:19:01.26 having a blood pressure reading that is 00:19:02.19\00:19:04.51 greater than or equal to 140/90 00:19:04.52\00:19:08.03 or being told that you do have 00:19:08.87\00:19:11.09 high blood pressure. Exhibiting HDL 00:19:11.10\00:19:15.22 cholesterol reading that are less than 00:19:15.23\00:19:17.31 35 mg/dl and triglyceride readings 00:19:17.32\00:19:21.30 greater than 250 mg/dl. Displaying 00:19:21.31\00:19:26.34 low physical activity levels and exhibiting 00:19:26.35\00:19:31.15 pre-diabetes, defined as having a fasting 00:19:31.16\00:19:34.74 glucose reading that is between 00:19:34.75\00:19:36.78 100 and 125 mg/dl. Near daily physical activity 00:19:36.79\00:19:45.14 performed at a comfortable intensity 00:19:45.94\00:19:48.11 and lasting between 20 to 45 minutes is 00:19:48.12\00:19:52.17 recommended for the Type 2 diabetic. 00:19:52.18\00:19:54.22 The importance of performing physical 00:19:55.80\00:19:57.67 activity as part of a regular routine 00:19:57.68\00:20:00.86 cannot be over emphasized since the 00:20:00.87\00:20:04.47 residual effects of a single exercise about 00:20:04.48\00:20:07.15 on insulin sensitivity and glucose control last 00:20:07.16\00:20:12.01 for only 1 to 2 days. Moreover, 00:20:12.02\00:20:15.87 weigh loss which can spur improvement 00:20:16.65\00:20:19.59 in insulin sensitivity is promoted with 00:20:19.60\00:20:23.14 daily exercise. Both large muscle 00:20:23.15\00:20:27.07 aerobic activities like walking, cycling 00:20:27.08\00:20:30.15 and swimming and high repetition resistance 00:20:30.16\00:20:33.67 training, both of these can enhance insulin 00:20:33.68\00:20:37.62 sensitivity and the overall management of 00:20:37.63\00:20:40.56 blood glucose levels. Interestingly, 00:20:40.57\00:20:44.56 skeletal muscle is the largest mass of insulin 00:20:44.57\00:20:48.45 sensitive tissue in the body. 00:20:48.46\00:20:50.11 Thus exercise training and daily physical 00:20:51.28\00:20:54.95 activity can help to alleviate insulin 00:20:54.96\00:20:57.94 resistance by preventing muscle atrophy 00:20:57.95\00:21:00.97 and building muscle mass. What is the 00:21:01.72\00:21:06.95 combined effect of diet and exercise 00:21:06.96\00:21:11.16 for the person with Type 2 diabetes? 00:21:11.17\00:21:13.20 This question was addressed in a report 00:21:14.08\00:21:16.48 published in 1994 that involve 652 patients 00:21:16.49\00:21:21.84 with Type 2 diabetes. Study participants 00:21:21.85\00:21:25.76 were part of a 26 day program 00:21:25.77\00:21:28.24 that featured a low fat, low salt, 00:21:28.25\00:21:31.43 low cholesterol, high fiber, 00:21:31.44\00:21:33.86 high carbohydrate primarily vegetarian 00:21:33.87\00:21:37.70 diet that was combined with walking 00:21:37.71\00:21:40.54 exercise lasting 1 to 2 hours per day. 00:21:40.55\00:21:43.88 Results from this study indicated that in 00:21:45.31\00:21:47.82 less than 1 month 39 percent of the 00:21:47.83\00:21:51.40 participants were able to stop their 00:21:51.41\00:21:53.27 insulin therapy in addition nearly 3/4 00:21:53.28\00:21:57.75 of the patients taking all hypoglycemic agents 00:21:57.76\00:22:01.07 were able to discontinue their use. 00:22:01.08\00:22:03.83 As shown in the following graphic 00:22:05.30\00:22:07.07 the program produced on average of 5 percent 00:22:07.08\00:22:12.06 loss in body weight, a 7 percent decrease 00:22:12.07\00:22:15.56 in systolic blood pressure, a 15 percent 00:22:15.57\00:22:19.24 reduction in fasting glucose levels, 00:22:19.25\00:22:21.47 a 22 percent reduction in total cholesterol 00:22:22.49\00:22:25.36 values and a 33 percent decrease in 00:22:25.37\00:22:28.42 triglyceride levels while it's difficult to 00:22:28.43\00:22:32.01 determine whether diet, physical activity 00:22:32.02\00:22:34.74 or weight loss was the primary factor 00:22:34.75\00:22:37.69 responsible for these improvements 00:22:37.70\00:22:39.64 and fitness status. These findings provide 00:22:39.65\00:22:42.84 clear support for the notion that positive 00:22:42.85\00:22:46.23 changes in lifestyle can improve the 00:22:46.24\00:22:49.04 health profile of Type 2 diabetics. 00:22:49.05\00:22:51.93 And in a more recent study published 00:22:52.82\00:22:54.62 in the New England Journal Medicine, 00:22:54.63\00:22:56.52 over 3200 persons with pre-diabetes 00:22:56.53\00:22:59.71 were assign randomly to 1 of 3 groups. 00:22:59.72\00:23:02.36 A placebo group, which received 00:23:03.13\00:23:05.51 standard lifestyle recommendations, 00:23:05.52\00:23:07.29 a medication group that received 00:23:07.30\00:23:10.34 standard lifestyle information 00:23:10.35\00:23:12.20 and an oral drug that increased insulin 00:23:12.21\00:23:15.10 sensitivity and a lifestyle modification 00:23:15.11\00:23:18.52 group that combined a healthy low calorie, 00:23:18.53\00:23:21.65 low fat diet with moderate physical 00:23:21.66\00:23:24.19 activity like brisk walking that was 00:23:24.20\00:23:27.37 performed for at least 150 minutes 00:23:27.38\00:23:29.49 per week which would translate into 00:23:29.50\00:23:32.08 30 minutes of activity, 5 days a week. 00:23:32.09\00:23:35.08 Data from this study revealed that persons 00:23:36.35\00:23:38.96 in the lifestyle modification group 00:23:38.97\00:23:41.42 exhibited a much greater change in weight 00:23:41.43\00:23:44.77 compare to the drug or placebo group. 00:23:44.78\00:23:47.69 Furthermore, the incidence of diabetes 00:23:48.72\00:23:51.55 was 58 percent lower in the lifestyle group 00:23:51.56\00:23:54.69 verses the placebo group and 39 percent 00:23:54.70\00:23:58.29 lower in the lifestyle group compare 00:23:58.30\00:24:00.58 to the medication group. Clearly, this study 00:24:00.59\00:24:05.21 demonstrates that simple lifestyle changes 00:24:05.22\00:24:07.57 can be quite effective in preventing the 00:24:07.58\00:24:10.29 onset of Type 2 diabetes among individuals 00:24:10.30\00:24:13.81 who are pre-diabetic. In earlier programs, 00:24:13.82\00:24:19.01 we've talked about the many health benefits 00:24:19.02\00:24:21.64 that come from walking. In a recent 00:24:21.65\00:24:25.90 investigation published in the Journal Archives 00:24:25.91\00:24:28.66 of Internal Medicine, the relationship between 00:24:28.67\00:24:31.89 physical activity and mortality was examined 00:24:31.90\00:24:34.80 in nearly 2900 adults with Type 2 diabetes. 00:24:34.81\00:24:38.93 Compared with inactive individuals 00:24:39.89\00:24:41.98 those who walk at least 2 hours per week 00:24:42.64\00:24:45.27 displayed a 39 percent lower death rate 00:24:45.28\00:24:48.31 from all causes and a 34 percent reduction 00:24:48.32\00:24:51.88 in mortality due to cardiovascular disease. 00:24:51.89\00:24:54.80 In those persons who walked at moderate 00:24:55.71\00:24:58.31 pace for 3 to 4 hours per week 00:24:58.32\00:25:01.03 or about 30 minutes per day, 00:25:01.04\00:25:02.96 mortality from all causes was reduced by 00:25:03.66\00:25:06.99 54 percent. This protective affect of 00:25:07.00\00:25:11.10 physical activity was observed for person 00:25:11.11\00:25:13.75 of varying sex, raise body mass index, 00:25:13.76\00:25:17.01 diabetes duration and physical limitation. 00:25:17.02\00:25:20.49 In an editorial that accompanied the article 00:25:21.29\00:25:24.42 Dr. Frank Hu from the Harvard School of Public 00:25:24.43\00:25:27.91 Health concluded that walking is probably 00:25:27.92\00:25:30.54 the "Best Medicine" for preventing 00:25:30.55\00:25:36.24 and treating diabetes. While regular 00:25:36.25\00:25:40.05 physical activity can confirm many 00:25:40.06\00:25:42.02 health benefits. The presence of specific 00:25:42.03\00:25:44.93 clinical conditions must be considered 00:25:44.94\00:25:46.94 when designing an exercise plan for 00:25:46.95\00:25:49.19 diabetics. For those individuals with the 00:25:49.20\00:25:52.02 complication of retinopathy or damaged 00:25:52.03\00:25:54.75 to the tiny blood vessels of the eye, 00:25:54.76\00:25:56.75 it's important to avoid strenuous high intensity 00:25:56.76\00:26:00.13 activities that involve breath holding 00:26:00.14\00:26:02.54 or the lowering or joining of the head. 00:26:02.55\00:26:04.84 Neuropathy or nerve damage is another 00:26:04.85\00:26:08.71 potential medical condition that must be 00:26:08.72\00:26:10.78 considered when recommending exercise 00:26:10.79\00:26:13.33 for the diabetic. In the case of peripheral 00:26:13.34\00:26:16.36 neuropathy which effects the extremities 00:26:16.37\00:26:19.03 especially the legs and feet, 00:26:19.04\00:26:20.84 one should avoid exercises that can cause 00:26:20.85\00:26:23.77 foot trauma like prolonged hiking 00:26:23.78\00:26:26.25 and jogging or walking on uneven surfaces. 00:26:26.26\00:26:30.29 For these individuals non-weight 00:26:31.41\00:26:33.56 bearing activities like cycling 00:26:33.57\00:26:35.38 and swimming can be a useful alternative. 00:26:35.39\00:26:38.05 Keep the feet clean and dry, choosing shoes 00:26:38.63\00:26:42.26 that fit properly and visually inspecting 00:26:42.27\00:26:45.08 the feet on a regular basis or other steps 00:26:45.09\00:26:47.69 that can be taken to lessen the consequences 00:26:47.70\00:26:50.25 of this condition. For the diabetic 00:26:50.26\00:26:53.11 who has high blood pressure heavy weight 00:26:53.12\00:26:55.38 lifting and breath holding should be 00:26:55.39\00:26:56.92 avoided and low-to-moderate 00:26:56.93\00:26:59.35 intensity exercise involving large muscle 00:26:59.36\00:27:01.74 groups like walking and cycling should be 00:27:01.75\00:27:04.45 emphasized. Diabetics can also suffer from 00:27:04.46\00:27:08.06 nephropathy which involves damage to the 00:27:08.07\00:27:11.32 small blood vessels in the kidneys. 00:27:11.33\00:27:13.21 In this case, one should avoid exercises 00:27:14.05\00:27:17.16 like weight lifting and high intensity 00:27:17.17\00:27:19.56 aerobic exercise that can increase 00:27:19.57\00:27:22.10 blood pressure to high levels. 00:27:22.11\00:27:23.89 For the active diabetic, exercise induce 00:27:24.84\00:27:28.03 hypoglycemia can be prevented by 00:27:28.04\00:27:30.81 monitoring glucose levels prior to 00:27:30.82\00:27:33.16 and following activity and by decreasing 00:27:33.17\00:27:36.72 insulin dosages based on the duration 00:27:36.73\00:27:39.57 and intensity of exercise as well as by 00:27:39.58\00:27:43.11 personal experience. To end let me just 00:27:43.12\00:27:48.61 recount a statement that someone told me 00:27:48.62\00:27:51.04 once who had diabetes. He told me Don, 00:27:51.05\00:27:54.31 when I walk on a regular basis I don't have 00:27:54.32\00:27:57.77 diabetes but when I fail to walk because 00:27:57.78\00:28:00.73 I'm too busy my diabetes returns. 00:28:00.74\00:28:03.97 There is so much power contained in being 00:28:03.98\00:28:07.87 physically active, remember that 00:28:07.88\00:28:09.81 and I'll see you next time. Goodbye. 00:28:09.82\00:28:13.00