The following program presents principles 00:00:01.98\00:00:02.95 designed to promot good health 00:00:02.96\00:00:03.93 and is not intended to take the place of 00:00:04.15\00:00:06.03 personalized professional care. 00:00:06.04\00:00:07.78 The opinions and ideas expressed 00:00:08.08\00:00:10.05 are those of the speaker. 00:00:10.28\00:00:11.40 Viewers are encouraged to draw their own 00:00:11.74\00:00:13.76 conclusion about the information presented. 00:00:13.77\00:00:15.93 Welcome to Wonderfully Made, 00:00:34.74\00:00:36.10 in today's segment of Wonderfully Made 00:00:36.88\00:00:38.96 we will look into the role of preventive 00:00:39.29\00:00:41.89 medicine in diabetes. 00:00:41.90\00:00:43.47 I am Dr. Meshach Samuel, I currently serve as 00:00:45.74\00:00:49.29 a Family practitioner and I enjoy doing 00:00:49.30\00:00:51.86 what I do in the field of primary care. 00:00:51.87\00:00:54.22 I love preventive medicine and in our study today 00:00:55.62\00:00:59.50 we will try to apply the principles of preventive 00:00:59.71\00:01:03.51 medicine in diabetes, why choose the subject 00:01:03.52\00:01:07.44 of diabetes, let me give you at least 00:01:07.45\00:01:10.15 three good reasons, firstly it is estimated 00:01:10.16\00:01:14.29 that approximately 17 million individuals 00:01:14.66\00:01:17.53 in the United States alone have diabetes 00:01:17.54\00:01:20.58 and it is a growing concern throughout the world. 00:01:21.14\00:01:23.55 Secondly, it is well known that a significant 00:01:24.67\00:01:28.25 fraction of those with Type 2 diabetes 00:01:28.26\00:01:31.35 remain undiagnosed. 00:01:31.66\00:01:33.40 You may want to ask yourself the question, 00:01:34.38\00:01:36.99 could I be one of those who has the disease 00:01:37.74\00:01:40.33 and is not aware of it? 00:01:40.34\00:01:41.64 And the third reason is that, 00:01:43.39\00:01:44.75 diabetes is a condition which in its early stages 00:01:44.76\00:01:48.80 presents with little or no symptoms 00:01:49.30\00:01:51.65 and if left undiagnosed will eventually lead 00:01:52.15\00:01:55.31 to major complications, disability and 00:01:55.32\00:01:58.55 premature death. And remember we will deal 00:01:58.56\00:02:02.72 with this subject of diabetes today 00:02:02.73\00:02:04.66 with emphasis on preventive medicine. 00:02:04.91\00:02:07.38 Before going any further let's cover 00:02:09.22\00:02:11.44 some basic information, 00:02:11.45\00:02:12.74 what is diabetes? 00:02:13.50\00:02:14.67 Diabetes is a condition in which there is excessive 00:02:16.22\00:02:19.22 amount of sugar in the blood, 00:02:19.23\00:02:20.89 and persistent excessive sugar in the blood 00:02:21.69\00:02:24.70 adversely affects our blood vessels and finally 00:02:25.00\00:02:29.46 results in damage of important organs 00:02:29.47\00:02:32.59 such as the kidneys, the eyes and 00:02:32.60\00:02:35.15 the nerves and so on. 00:02:35.16\00:02:36.27 Let's now review briefly the physiology, 00:02:38.07\00:02:41.41 that is the processes that take place 00:02:41.42\00:02:44.40 in the body relating to blood sugar. 00:02:44.71\00:02:47.19 The cells in our body need glucose, 00:02:48.63\00:02:51.41 which is the simplest form of sugar 00:02:51.68\00:02:53.60 that is broken down to obtain energy. 00:02:53.88\00:02:56.40 The body tries to maintain what we call 00:02:57.93\00:02:59.98 normal range of blood sugar 00:03:00.16\00:03:02.61 in a normal healthy individual 00:03:04.82\00:03:06.51 soon after a meal especially one that 00:03:07.10\00:03:09.92 is reach in carbohydrates, 00:03:09.93\00:03:11.35 glucose from the diet enters the blood stream 00:03:12.85\00:03:16.07 and as a result blood sugar levels go up. 00:03:16.41\00:03:19.31 And in response to the raising levels of 00:03:20.91\00:03:23.50 glucose in the blood, the pancreas, 00:03:23.51\00:03:26.36 an important organ in the body, 00:03:26.37\00:03:28.19 produces a substance called insulin. 00:03:28.46\00:03:31.60 Now the most important function for insulin 00:03:32.97\00:03:35.76 is to lower the blood glucose levels 00:03:36.19\00:03:39.40 and it does this in two ways. 00:03:40.36\00:03:42.24 Firstly, the most important one, 00:03:43.76\00:03:45.05 insulin enters into the cells of the 00:03:45.48\00:03:48.16 various tissues and helps the cell 00:03:48.17\00:03:51.03 use up the glucose 00:03:51.31\00:03:52.41 and secondly insulin also triggers the liver 00:03:54.51\00:03:58.73 to take up the excess glucose in the blood 00:03:58.98\00:04:01.62 so that it can be stored and later released 00:04:01.97\00:04:05.09 when there is a need. 00:04:05.10\00:04:06.15 Now, there are other organs, 00:04:07.97\00:04:09.17 enzymes and hormones that play a role 00:04:09.36\00:04:11.93 in processing and altering the blood glucose levels 00:04:12.11\00:04:16.15 but all these factors work together to maintain 00:04:17.73\00:04:20.99 a normal range of blood sugar in our body. 00:04:21.00\00:04:24.69 Unfortunately we live in a world where things 00:04:25.36\00:04:29.22 do go wrong and this applies to the 00:04:29.23\00:04:32.59 way our body functions. 00:04:32.60\00:04:34.38 It could happen as a result of something 00:04:35.15\00:04:37.45 we have brought up on ourselves 00:04:37.46\00:04:39.05 or sometimes due to factors beyond our control. 00:04:39.50\00:04:43.15 In type 1 diabetes the particular cells of the 00:04:44.83\00:04:48.84 pancreas which produce insulin are damaged 00:04:48.85\00:04:52.59 or destroyed and as a result 00:04:53.56\00:04:55.61 there is no insulin production, 00:04:55.87\00:04:57.71 this often happens in the early 00:04:58.78\00:05:01.94 part of our lives. 00:05:01.95\00:05:02.92 There are several explanations 00:05:03.83\00:05:05.38 of how this happens, 00:05:05.39\00:05:06.81 however when a significant number 00:05:07.17\00:05:09.65 of cells in the pancreas that produces 00:05:09.66\00:05:12.13 the insulin are destroyed type 1 diabetes occurs. 00:05:12.14\00:05:16.12 Now, let us see what happen in individuals 00:05:16.80\00:05:19.50 with type 2 diabetes which is what 00:05:19.51\00:05:21.86 we're going to be talking about mostly today. 00:05:21.87\00:05:23.95 We have seen earlier that glucose and insulin 00:05:25.36\00:05:29.19 from the blood has to get into the cells 00:05:29.20\00:05:32.23 where the glucose is broken down 00:05:32.36\00:05:34.13 and used up to obtain energy. 00:05:34.26\00:05:36.28 Normally, insulin enters into the cells 00:05:37.49\00:05:40.64 whenever there is a need for glucose 00:05:41.24\00:05:43.39 to be broken down but in type 2 diabetes, 00:05:43.40\00:05:46.74 there is a gradual build up of some form of 00:05:46.94\00:05:51.11 resistance making it difficult for insulin 00:05:51.12\00:05:54.15 to get into the cells. 00:05:54.16\00:05:55.45 So, we see that individuals prone to 00:05:56.04\00:05:58.95 type 2 diabetes tend to develop what is known as 00:05:58.96\00:06:02.74 insulin resistance. When insulin cannot be utilized 00:06:02.75\00:06:07.28 due to resistance build up, 00:06:07.29\00:06:08.87 blood sugar levels remain high. 00:06:09.60\00:06:11.41 And the pancreas is now constantly stimulated 00:06:12.89\00:06:16.16 due to the persistently elevated blood sugar 00:06:16.54\00:06:18.85 levels and the over stimulated pancreas 00:06:18.86\00:06:22.51 now produces more and more insulin because 00:06:22.90\00:06:26.16 it appears that a larger amount of insulin 00:06:26.17\00:06:29.42 is needed to overcome the resistance. 00:06:29.43\00:06:31.76 And in the early stages of type 2 diabetes 00:06:33.83\00:06:36.09 this seems to work but as the resistance 00:06:36.10\00:06:39.91 continues to increase the pancreas at some point 00:06:39.92\00:06:44.26 is unable to meet the demands 00:06:44.61\00:06:46.79 and appears to give up. 00:06:46.96\00:06:48.22 So, we end up with two problems 00:06:49.43\00:06:50.99 in type 2 diabetes, one the gradual 00:06:51.00\00:06:54.64 progressive development of insulin resistance 00:06:54.65\00:06:57.27 and two the gradual decrease in insulin 00:06:57.55\00:07:01.68 production by the pancreas due to the 00:07:01.69\00:07:04.96 excessive demands placed on it. 00:07:04.97\00:07:06.95 The end result is that glucose 00:07:08.65\00:07:11.26 is not broken down and blood glucose 00:07:11.27\00:07:13.62 levels begin to rise, 00:07:13.63\00:07:15.35 leading to type 2 diabetes. 00:07:15.72\00:07:17.54 The risk of developing this form of diabetes 00:07:18.36\00:07:21.47 is greater in those with a family history 00:07:21.48\00:07:24.37 of type 2 diabetes, suggesting a stronger 00:07:24.38\00:07:28.10 genetic component than in type 1 diabetes. 00:07:28.11\00:07:31.32 We have looked into what diabetes is, 00:07:32.14\00:07:34.53 and what happens in the body 00:07:34.94\00:07:36.97 when one has diabetes. 00:07:37.09\00:07:39.59 Now, let us take a little look about 00:07:40.89\00:07:44.80 how the disease progresses in an 00:07:44.81\00:07:47.80 individual, from its onset to its termination, 00:07:47.81\00:07:52.82 either as a cure or disability or even death. 00:07:52.83\00:07:56.61 Now, we call this the study of the 00:07:57.22\00:08:00.27 natural history of diabetes. 00:08:00.28\00:08:02.33 Let us see if we can illustrate 00:08:03.95\00:08:05.51 this with a diagram. 00:08:05.52\00:08:06.87 The horizontal line that you see on your screen 00:08:07.87\00:08:10.42 represents a time line a period in one's life. 00:08:10.71\00:08:14.06 And the small vertical line that intersects 00:08:15.19\00:08:17.90 it represents the point of onset of the disease 00:08:18.08\00:08:20.76 in that particular individual. 00:08:21.28\00:08:22.98 Now, we have the time line divided into two, 00:08:24.15\00:08:27.27 the line before the point of onset represents 00:08:27.63\00:08:31.56 the diabetes free stage 00:08:31.89\00:08:34.48 that is there is no diabetes, 00:08:35.06\00:08:36.71 and the period beyond the point of onset 00:08:36.97\00:08:39.82 of the disease represents the diabetes stage. 00:08:39.83\00:08:43.84 Now, let us take a closer 00:08:45.33\00:08:46.76 look at the diabetic stage. 00:08:46.77\00:08:48.84 You will recall that when we talked about 00:08:50.42\00:08:52.79 the prevalence of diabetes we learned 00:08:52.80\00:08:55.54 that a significant number of those with 00:08:55.85\00:08:58.15 type 2 diabetes do not know that they have 00:08:58.16\00:09:01.48 that type of disease. And this is because 00:09:01.49\00:09:05.04 although the disease process has started, 00:09:05.28\00:09:07.75 they have not developed any symptoms of the 00:09:07.94\00:09:11.22 disease and therefore they remain unaware of it. 00:09:11.23\00:09:14.15 Evidently, in type 2 diabetes after 00:09:16.25\00:09:19.72 the onset of the disease process, 00:09:19.73\00:09:21.53 there is a period of time when the patient 00:09:21.68\00:09:25.31 is free of symptoms. If the disease process 00:09:25.32\00:09:29.41 is allowed to proceed unchecked at some point 00:09:29.42\00:09:33.85 symptoms will begin to show up. 00:09:33.86\00:09:35.67 So, we now see that diabetes stage 00:09:37.46\00:09:40.72 or the disease stage can really be divided 00:09:40.73\00:09:44.30 again into two stages, one the early stage 00:09:44.31\00:09:47.17 in which the disease process has started 00:09:47.40\00:09:49.91 but there are no symptoms and this period 00:09:49.92\00:09:53.60 we refer to as the pre-diabetic stage 00:09:53.61\00:09:56.59 and then we have the late stage, 00:09:57.85\00:09:59.48 which is the true diabetic stage. 00:09:59.49\00:10:01.36 Let us review the natural history 00:10:03.64\00:10:05.21 of diabetes again. From the natural history 00:10:05.22\00:10:08.55 of diabetes we see at least 00:10:08.56\00:10:10.04 three different stages. 00:10:10.05\00:10:11.96 One could be in the period before the onset 00:10:13.46\00:10:16.59 of the disease representing disease 00:10:16.60\00:10:19.46 free or diabetic free state, 00:10:19.47\00:10:22.05 or one could be in the period immediately 00:10:23.26\00:10:26.59 after the onset of the disease representing 00:10:26.60\00:10:29.33 the early stages of diabetes without 00:10:29.34\00:10:32.22 any symptoms and this we refer to as the 00:10:32.23\00:10:35.48 pre-diabetic state or we could find ourselves 00:10:35.49\00:10:39.95 in the latter part of the time line namely 00:10:40.22\00:10:42.63 the diabetic state. If we should extend this line, 00:10:42.64\00:10:47.64 the time line and leave this diabetic state 00:10:48.19\00:10:51.83 unchecked it will lead to disability 00:10:51.84\00:10:55.03 and eventually premature death. 00:10:55.32\00:10:57.07 So, the first step in dealing with the question 00:10:58.52\00:11:01.05 of diabetes is to know where you stand 00:11:01.06\00:11:04.14 in the natural history of diabetes. 00:11:04.36\00:11:06.38 In other words, are you in the diabetes 00:11:06.70\00:11:09.81 free state or are you in the pre-diabetic state 00:11:09.82\00:11:14.68 or are you in the diabetic state? 00:11:15.08\00:11:17.74 I believe that God desires for all of us 00:11:19.38\00:11:21.96 to be in the diabetes free state, 00:11:22.38\00:11:25.33 but how do we find out where we stand 00:11:26.77\00:11:28.58 in the line of natural history of disease? 00:11:29.00\00:11:31.21 One way to guess is to see if you have 00:11:33.10\00:11:37.17 any symptoms, what are some 00:11:37.18\00:11:39.86 of the symptoms of diabetes? 00:11:39.87\00:11:41.44 Fatigue, excessive thirst, excessive urination, 00:11:43.22\00:11:47.33 unexplained weight loss and sometimes 00:11:47.79\00:11:50.94 blurred vision. Now, there are two problems 00:11:51.12\00:11:55.04 if you decide to guess and go by symptoms, 00:11:55.05\00:11:58.10 the first one is that most of these symptoms 00:11:58.51\00:12:01.62 are non-specific for diabetes, 00:12:01.63\00:12:03.94 so we really can't go by that and the second 00:12:04.63\00:12:07.58 one which is a more important one is that 00:12:07.59\00:12:10.42 most individuals with undiagnosed diabetes 00:12:10.43\00:12:13.68 remain asymptomatic. 00:12:14.00\00:12:16.04 So, we see a very disturbing 00:12:18.38\00:12:20.14 picture here, you could be in the diabetes 00:12:20.15\00:12:23.18 free state or in the pre-diabetic state 00:12:23.19\00:12:27.25 or in the late diabetic state and yet have 00:12:28.05\00:12:31.45 no symptoms at all. 00:12:31.46\00:12:32.90 So the single best way to find out where 00:12:34.94\00:12:37.82 we stand in regard to diabetes is to do a 00:12:37.83\00:12:41.14 blood test and see what the blood sugar levels are. 00:12:41.15\00:12:43.69 We call this process screening. 00:12:44.96\00:12:47.31 Screening is a process where we search for 00:12:49.24\00:12:51.79 unrecognized disease or defect. 00:12:51.80\00:12:54.79 The term screening is not new to many of us. 00:12:56.62\00:12:59.21 You may have heard about screening 00:13:00.05\00:13:01.57 for breast cancer, screening for 00:13:01.58\00:13:03.83 colon cancer or prostate cancer and so on. 00:13:03.84\00:13:06.29 But someone would like to ask, 00:13:06.89\00:13:09.47 is it really important to be screened for diabetes? 00:13:11.30\00:13:14.92 The answer is yes. Undiagnosed diabetes 00:13:16.16\00:13:20.04 is very common, current estimates suggest 00:13:20.05\00:13:23.35 that up to one third of adults with diabetes 00:13:23.36\00:13:26.97 in the United States remain undiagnosed 00:13:26.98\00:13:30.31 and it has also being found that upto 00:13:32.87\00:13:35.91 50 percent of those with diabetes were diagnosed 00:13:35.92\00:13:40.04 after complications of diabetes developed 00:13:40.36\00:13:42.98 and here's the most important reason. 00:13:44.68\00:13:46.24 Screening for diabetes offers the potential 00:13:47.34\00:13:50.64 to not only diagnose and intervene at an 00:13:51.54\00:13:54.15 early stage that is before the complication 00:13:54.16\00:13:57.07 is developed but also screening offers 00:13:57.08\00:14:01.13 the possibility of preventing diabetes itself 00:14:01.14\00:14:05.19 We must ask the question who should be 00:14:07.80\00:14:11.67 screened for type 2 diabetes. 00:14:11.68\00:14:13.77 We need to remember that by screening 00:14:15.38\00:14:17.77 we are looking for people with unrecognized 00:14:18.00\00:14:21.12 disease and the term screening is usually 00:14:21.13\00:14:26.44 applied to a population at risk. 00:14:26.45\00:14:29.00 So, there is no need for everyone to be screened, 00:14:30.98\00:14:33.21 it is recommended for the population at risk. 00:14:33.97\00:14:37.34 What do we mean by population at risk? 00:14:38.68\00:14:40.71 It simply refers to individuals who have risk 00:14:42.13\00:14:45.86 factors for developing the disease. 00:14:45.87\00:14:48.49 Now, based on several studies of the 00:14:49.63\00:14:52.44 many factors that are associated with diabetes, 00:14:52.45\00:14:55.28 the American Diabetic Association has come up 00:14:56.09\00:14:59.28 with some guidelines for screening. 00:14:59.29\00:15:01.99 In other words, they have identified some important 00:15:03.05\00:15:07.23 risk factors and based on the presence 00:15:07.24\00:15:10.83 or the absence of these risk factors 00:15:10.84\00:15:13.74 the commendations are made as to 00:15:13.89\00:15:16.22 who should be screened. 00:15:16.23\00:15:17.21 So, here's what's recommended? 00:15:19.12\00:15:20.40 Number one if you are of 45 years of age 00:15:21.23\00:15:25.23 or more you should be screened for 00:15:25.24\00:15:28.19 type 2 diabetes and if the result is normal 00:15:28.20\00:15:30.88 it should be repeated at three year intervals. 00:15:31.33\00:15:34.37 And number two, testing should be considered 00:15:36.29\00:15:39.40 at the younger age or be carried out more 00:15:39.41\00:15:42.96 frequently if you are obese or overweight 00:15:42.97\00:15:46.83 and you have one of the following six risk factors 00:15:48.02\00:15:51.76 that I will shortly mention. 00:15:51.77\00:15:53.55 What are these six risk factors? Number one, 00:15:54.81\00:15:56.69 if you have a first degree relative with diabetes. 00:15:58.16\00:16:02.02 Number two, if you belong to a high risk 00:16:03.49\00:16:06.75 ethnic group example African-American, 00:16:06.96\00:16:10.93 Pacific Islander, Native American 00:16:11.46\00:16:14.30 or an Asian American. And number three, 00:16:14.31\00:16:17.64 if you have hypertension, 00:16:18.76\00:16:20.67 that is high blood pressure. 00:16:20.87\00:16:22.12 And number four, if you have abnormal 00:16:23.60\00:16:26.54 cholesterol levels most importantly 00:16:26.55\00:16:29.20 low HDL Cholesterol or high levels 00:16:29.21\00:16:34.07 of triglycerides. Number five, 00:16:34.08\00:16:36.82 if you are habitually, physically inactive. 00:16:37.69\00:16:41.36 And the last one number six, 00:16:43.52\00:16:44.84 and this one pertains to women, 00:16:45.00\00:16:46.73 if you are a mother of an infant with 00:16:47.02\00:16:50.74 a birth rate of greater than 9 pounds. 00:16:50.75\00:16:53.36 So, if you have any of these six risk factors 00:16:55.04\00:16:58.02 and you are obese or overweight, 00:16:58.03\00:17:02.02 your chances of developing diabetes 00:17:02.24\00:17:04.55 is higher than the normal population 00:17:04.56\00:17:06.96 and it is recommended that you be screened 00:17:07.59\00:17:10.68 as soon as possible and not wait till 00:17:10.69\00:17:12.99 your 45 years of age. 00:17:13.00\00:17:14.24 We have seen that screening is important 00:17:15.33\00:17:17.88 and we have also seen as to 00:17:19.12\00:17:21.19 who should be screened. 00:17:21.20\00:17:22.25 Now, we ask the question, 00:17:23.20\00:17:24.40 how do we screen for diabetes, 00:17:24.71\00:17:26.92 several different tests can be done, 00:17:28.24\00:17:30.12 but for the purpose of screening 00:17:30.88\00:17:32.40 we always choose the simplest test, 00:17:32.41\00:17:35.12 a morning fasting blood sample is tested 00:17:35.89\00:17:39.25 for glucose levels. If the value obtained 00:17:39.26\00:17:43.28 is less than a 100 mgs, 00:17:43.29\00:17:45.36 it may be considered normal. 00:17:46.00\00:17:47.97 If on testing we get a value of a 00:17:49.55\00:17:52.57 126 mgs or above, it is considered abnormal 00:17:52.58\00:17:57.80 and if repeat tests confirms this value 00:17:59.10\00:18:02.24 the individual probably has diabetes. 00:18:02.25\00:18:04.57 What about values between a 126 and a 100 mgs, 00:18:06.03\00:18:10.66 this is considered impaired, 00:18:11.30\00:18:13.46 so we see three groups on screening. 00:18:14.31\00:18:17.03 The first one normal and then we said 00:18:17.85\00:18:20.85 talk about abnormal and the third one impaired, 00:18:20.86\00:18:24.08 let's review these numbers once again 00:18:25.56\00:18:27.34 and also see how they correspond to the 00:18:27.92\00:18:31.83 natural history of diabetes that 00:18:31.84\00:18:34.32 we talked about earlier. 00:18:34.33\00:18:35.38 The fasting blood sugar value of less than 00:18:37.10\00:18:39.97 a 100 mgs would be considered normal, 00:18:39.98\00:18:43.05 this will correspond to the diabetic free state 00:18:43.71\00:18:46.71 of the natural history of diabetes. 00:18:47.12\00:18:49.24 A value of 126 mgs or above is considered 00:18:50.00\00:18:55.10 abnormal and this would correspond 00:18:55.11\00:18:57.77 to the disease phase or the diabetic state 00:18:58.00\00:19:01.23 of the natural history of diabetes 00:19:01.99\00:19:03.89 and values between 126 mgs and 100 mgs 00:19:05.07\00:19:10.50 would be considered impaired 00:19:10.76\00:19:12.90 and it would correspond to the early stages 00:19:13.59\00:19:16.79 of the disease phase or the pre-diabetic state 00:19:16.80\00:19:20.37 in the natural history of diabetes. 00:19:20.71\00:19:22.73 We now move on to the most important part 00:19:24.70\00:19:29.03 of our study on preventive medicine 00:19:29.04\00:19:31.31 in diabetes and that is 00:19:31.70\00:19:34.35 intervention or treatment. 00:19:34.84\00:19:37.04 Intervention will obviously depend upon 00:19:38.77\00:19:41.06 where you find yourself on the time line 00:19:41.07\00:19:43.98 of the natural history of diabetes. 00:19:43.99\00:19:45.72 Let us say you were screened for diabetes 00:19:46.29\00:19:49.13 and found the test to be normal, 00:19:49.14\00:19:51.38 that is less than a 100 mgs. 00:19:51.52\00:19:53.35 You may now consider yourself in the 00:19:54.23\00:19:56.61 diabetes free state. Is there anything that 00:19:56.62\00:20:01.65 you need to do at this stage? 00:20:01.66\00:20:02.73 The answer is yes. 00:20:03.44\00:20:04.74 The interventions at this stage are actions 00:20:06.19\00:20:09.17 that would enable you to preserve that 00:20:09.18\00:20:11.71 state of health, that is, being free of diabetes 00:20:11.72\00:20:15.54 and also continue with actions that will promote 00:20:16.08\00:20:19.98 better health and the way we do this is by 00:20:19.99\00:20:23.89 following the natural laws of health. 00:20:23.90\00:20:26.07 Eating a well balance diet, 00:20:26.75\00:20:28.31 exercising regularly, by the proper use of water, 00:20:28.57\00:20:33.72 fresh air, sunshine and ensuring adequate rest, 00:20:34.06\00:20:38.59 upstaining from things that we know are harmful 00:20:38.98\00:20:42.15 to the body and living a life free of worry 00:20:42.16\00:20:45.56 and stress by trusting in God. 00:20:45.57\00:20:48.35 This is how God meant for us to preserve health 00:20:50.12\00:20:52.94 and promote health and this is true primary 00:20:52.95\00:20:59.37 prevention in diabetes after that matter 00:20:59.38\00:21:02.35 with regard to any disease. 00:21:02.64\00:21:03.87 But what if on screening you find yourself 00:21:05.58\00:21:08.23 in the early stage that is the pre-diabetic state? 00:21:08.62\00:21:13.32 This is where screening really pays off, 00:21:15.39\00:21:17.43 in fact screening is really aimed 00:21:18.78\00:21:21.16 at picking up this group. 00:21:21.17\00:21:22.53 In finding some one in the pre-diabetic state 00:21:23.98\00:21:26.94 by screening we have actually made an early 00:21:26.95\00:21:30.38 diagnosis of diabetes, early diagnosis along with 00:21:30.39\00:21:36.02 appropriate treatment forms the basis 00:21:36.03\00:21:38.55 for secondary prevention in preventive medicine. 00:21:38.56\00:21:41.83 So, now lets see what is the appropriate 00:21:42.69\00:21:45.37 treatment for those in the pre-diabetic state, 00:21:45.38\00:21:48.57 the American Diabetic Association recommends 00:21:49.56\00:21:52.32 what is called the therapeutic lifestyle 00:21:52.33\00:21:54.89 changes and there are four recommendations 00:21:54.90\00:21:57.49 under the therapeutic lifestyle changes. 00:21:57.50\00:21:59.70 Number one, carbohydrate counting, 00:22:00.32\00:22:02.57 because carbohydrates is, in our diet has the 00:22:03.17\00:22:07.36 largest influence on glucose. Number two, 00:22:07.37\00:22:11.02 calorie restriction, this can done effectively 00:22:11.44\00:22:15.10 by cutting down dietary fact. 00:22:15.11\00:22:17.06 Numbe three, weight reduction, 00:22:18.54\00:22:20.59 diabetes is closely associated with obesity, 00:22:21.92\00:22:24.60 we have noticed earlier that obesity 00:22:25.24\00:22:28.62 is an important risk factor, special reference 00:22:29.11\00:22:33.18 is made to central obesity that is a waist 00:22:33.19\00:22:36.54 circumference greater than 40 inches in men 00:22:36.55\00:22:39.13 and 35 inches for women has been found 00:22:40.01\00:22:43.43 to co-relate with insulin resistance. 00:22:43.44\00:22:46.05 And the fourth one, exercise, exercise 00:22:48.05\00:22:51.41 enhances or facilitates muscle intake of insulin 00:22:51.42\00:22:55.68 and reduces insulin resistance. 00:22:55.98\00:22:58.33 A recent study found that 60 percent 00:22:59.77\00:23:01.89 of Americans do not engage in any moderate 00:23:01.90\00:23:04.90 level activity and that 30 percent do 00:23:04.91\00:23:08.18 not exercise at all. 00:23:08.19\00:23:09.44 So, we see that carbohydrate counting, 00:23:10.62\00:23:13.08 calorie restriction, weight reduction 00:23:13.38\00:23:16.10 and exercise form the basis of therapeutic 00:23:16.33\00:23:20.14 lifestyle changes recommended by the 00:23:20.15\00:23:22.43 American Diabetic Association. 00:23:22.44\00:23:23.87 Now, let me stress here that these four 00:23:26.46\00:23:28.72 recommendations for the pre-diabetic state 00:23:28.73\00:23:31.33 is an addition to the interventions 00:23:31.48\00:23:34.28 we have mentioned for those 00:23:34.29\00:23:36.11 in the diabetic free state, 00:23:36.12\00:23:38.38 that is along with the therapeutic lifestyle 00:23:38.43\00:23:41.75 changes one must follow the natural laws 00:23:41.76\00:23:44.82 of health as well. 00:23:44.83\00:23:45.80 Let's move on to the advanced disease stage 00:23:47.23\00:23:50.34 what if on screening your results confirm 00:23:50.93\00:23:53.69 blood sugar levels that are very high. 00:23:53.97\00:23:56.21 One must initiate aggressive medical 00:23:57.63\00:24:00.86 treatment as soon as possible, 00:24:00.87\00:24:02.91 it is important that we do not leave elevated 00:24:04.15\00:24:07.30 blood sugar levels to go unchecked 00:24:07.31\00:24:09.35 for long periods of time, medications are available 00:24:09.36\00:24:13.55 that lowers insulin resistance which we have 00:24:13.56\00:24:16.80 learned is one of the reasons for developing 00:24:16.81\00:24:18.96 type 2 diabetes. Medications are available 00:24:18.97\00:24:22.68 that stimulate the pancreas to put out 00:24:22.69\00:24:25.05 more insulin. We may even have to resort 00:24:25.06\00:24:28.95 to insulin administration by injections to replace 00:24:28.96\00:24:32.52 the natural insulin that the body is lacking. 00:24:32.53\00:24:35.56 Again, let me emphasize that the aggressive 00:24:37.18\00:24:39.56 medical treatment is to be accompanied 00:24:39.57\00:24:41.80 by the therapeutic lifestyle changes that 00:24:41.81\00:24:44.30 we talked about for those in the early 00:24:44.31\00:24:46.74 disease stage and we also need to the follow 00:24:46.75\00:24:49.70 the natural laws of health that were mentioned 00:24:49.71\00:24:52.60 for those in the diabetes free state. 00:24:52.61\00:24:55.69 This where many miss the mark, 00:24:56.44\00:24:58.27 we must realize that in order for God to bless 00:24:59.18\00:25:02.24 the treatments that we take, 00:25:02.25\00:25:03.98 we must first follow the natural laws of health. 00:25:04.38\00:25:07.71 No matter what approach we take in our treatment, 00:25:09.72\00:25:13.06 our goal should be to move back from the 00:25:14.76\00:25:17.62 late stage of diabetes, 00:25:17.63\00:25:19.21 if you find yourself there, 00:25:19.47\00:25:20.85 to the pre-diabetic state. 00:25:21.39\00:25:23.08 We do that by starting on aggressive 00:25:24.79\00:25:26.87 medical treatment and careful monitoring of 00:25:27.01\00:25:30.56 blood sugar levels. Self monitoring of blood 00:25:30.57\00:25:33.86 sugar has been made simple and patients 00:25:33.87\00:25:36.78 are able to do this at their home. 00:25:36.79\00:25:38.14 Patients on medications are encouraged to check 00:25:39.76\00:25:43.23 their blood sugars frequently 00:25:43.24\00:25:45.44 and when we have brought the numbers 00:25:46.90\00:25:49.27 to the pre-diabetic state, 00:25:49.61\00:25:51.82 we should then try to move from there to the 00:25:52.38\00:25:55.37 disease free state and this could be done 00:25:55.38\00:25:58.30 by following the therapeutic 00:25:58.78\00:26:00.06 lifestyle changes. 00:26:00.07\00:26:01.59 Once we obtain the desired level of 00:26:02.92\00:26:04.74 blood sugar control, we can try and wean 00:26:04.75\00:26:08.00 ourselves off the aggressive medical 00:26:08.01\00:26:10.40 treatments and continue with therapeutic 00:26:10.41\00:26:14.26 lifestyle changes, which is carbohydrates counting, 00:26:14.45\00:26:18.14 calorie restriction weight loss and exercise, 00:26:18.42\00:26:22.81 and of course we always need to continue 00:26:23.14\00:26:26.06 following the natural laws of health to preserve 00:26:26.31\00:26:29.58 and promote health. Which would include a 00:26:29.59\00:26:34.57 well balanced diet adequate rest, 00:26:34.58\00:26:37.19 proper use of water, fresh air and sunshine, 00:26:37.57\00:26:40.96 and attempting to live a life free of stress 00:26:41.23\00:26:44.68 by trusting in God. So, we need to understand 00:26:44.98\00:26:48.84 three steps in dealing with diabetes, 00:26:48.85\00:26:51.04 first, know where you stand in the natural 00:26:51.05\00:26:54.16 history of diabetes by screening, 00:26:54.17\00:26:56.61 then we make appropriate interventions. 00:26:57.87\00:27:00.42 When we study and understand the intricate 00:27:02.62\00:27:05.58 ways in which our body functions 00:27:05.59\00:27:08.01 and the way our body takes care of its energy 00:27:08.67\00:27:12.86 requirements using glucose from the diet, 00:27:12.87\00:27:15.21 and how the body regulates and maintains 00:27:15.52\00:27:19.37 a normal blood sugar level, we are reminded of 00:27:19.38\00:27:23.23 the verse in the Bible in the 139th Psalm, 00:27:23.24\00:27:25.70 I will praise thee; for I am fearfully 00:27:26.03\00:27:29.56 and wonderfully made. 00:27:29.88\00:27:31.25 One of the ways we could praise God is by 00:27:32.96\00:27:36.22 following the principles of preventive medicine 00:27:36.23\00:27:39.21 and learning how to take steps to prevent 00:27:39.77\00:27:43.82 the development of diabetes and the 00:27:44.28\00:27:47.24 progression of diabetes or for that matter 00:27:47.25\00:27:49.62 any disease, in order for us to preserve 00:27:49.91\00:27:54.67 and promote health that God has given us. 00:27:55.01\00:27:57.51 I hope that this presentation 00:27:59.39\00:28:01.01 has helped you understand a little more 00:28:01.02\00:28:03.48 clearly as to what diabetes is and 00:28:03.49\00:28:06.80 how you could prevent it from onset. 00:28:06.81\00:28:08.96 Thanks for joining me today in our study 00:28:09.29\00:28:11.79 of preventive medicine in diabetes. 00:28:11.80\00:28:14.27