Music...
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Happy to be here for
today's presentation,
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it's one of the more
important aspects of our lives
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that we're going to
talk about: Sleep...
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and yet, as important as it is,
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it's one of the least understood
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but in the last decade or so,
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there's been a lot
of research on sleep
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and we now understand much more
than we ever understood before.
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Sleep... we often
think of sleep as rest
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because we wake up in the
morning rested and refreshed
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but the brain
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isn't actually resting during
the time that we're sleeping,
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it's actually very active...
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it just has
different tasks that it's doing
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and these tasks do not
want us to be conscious
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but unconscious
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and so, we are
asleep during that time
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but the brain
isn't actually resting,
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it's working really
hard during that time
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and if it were not for the work
that the brain was doing then,
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you wouldn't be able to continue
with your conscious life
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in this world for the
rest of the coming day.
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If you live to be 90 years old,
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you will have spent 30
years of your life unconscious
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in the state of sleep.
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It's absolutely essential...
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you can't avoid
it... we need it.
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Did you get
enough sleep last week?
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Can you recall the
last time you woke up
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without an alarm
clock... feeling refreshed...
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not needing any Caffeine?
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Two thirds of us
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do not get the recommended
eight hours of sleep.
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Somewhere between
seven and nine hours
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is the ideal
number for most people
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and it's absolutely
essential to get this sleep...
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the effects of sleep deprivation
are very harmful on the body.
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One of the parts of us that is
affected is the immune system.
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Sleep deprivation
demolishes our immune system...
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sets us up for
increased infections...
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the cells of your immune system
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need to be refurbished
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and they are refurbished
during the time of sleep.
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They need to build up all
of the ammunition and supplies
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to carry on the battle
against bacteria and viruses.
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It's during this time
that they make up the various
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communicator molecules
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and sending the
messages back and forth
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and so, it's
absolutely essential
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if we're going to be successful
in fighting off the bacteria
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and other
microbes that can infect us
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and cause serious harm...
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we need good sound sleep...
eight hours of it every night
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but it's not only
fighting infections...
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your
immune-system's job is not only
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recognize foreign
invaders from outside your body,
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but also to recognize invaders
from inside... rebels...
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the cancer cells...
cells that have altered change
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that are no longer
behaving as they should,
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the immune system needs to
recognize those and destroy them
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and if you get a good sleep,
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usually they're able
to carry on their job.
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We're obviously
making cancer cells
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on a regular
basis in our body...
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the immune system recognizes
them and destroys them
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and we're okay.
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It's only when the
immune system fails
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and the cancer can
take off and spread and grow
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that we end up getting diagnosed
with cancer down the road.
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Pause...
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Alzheimer's disease...
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sleep deprivation is one of
the key lifestyle risk factors
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determining whether or
not you're going to develop
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Alzheimer's disease.
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Devastating condition...
the brain is broken down
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and shrinks away and
we lose cognitive function
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we lose memory and...
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not just memory but all of
the other parts of the brain
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seem to go with it and
eventually we will die and...
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because we just can't carry
on the basic life functions
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of the body
without the brain directing
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and
coordinating those functions.
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Pause...
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We know that sleep deprivation
is one of those risk factors...
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if you're not
getting enough sleep,
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you are
definitely at higher risk
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for getting Alzheimer's disease.
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It's a major risk factor
in coronary artery disease...
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heart attacks... strokes...
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the number one cause
of death in this country.
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If you don't want those big
tombstones on your EKG here,
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these big raised
tombstones here...
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those...
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what we call STEMI
an S T Elevation M I
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from occlusive infarct in one
of the arteries of your heart.
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It's a distinctive EKG finding
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and you don't
want those on your EKG
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because if you do, you
may also find the tombstone
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over your grave soon...
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they go along together there.
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Sleep deprivation actually
increases insulin resistance.
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In other words, moves
you into a pre-Diabetic state
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and can push you on down
that road towards Diabetes.
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It's interesting...
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you can take a group of
healthy college students
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cutting back on
their sleep deprivation
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so, they're getting less
than six hours of sleep a night
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and by the end of one week,
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you can check
their blood-sugar levels
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and they're
already going into this...
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what we would be
measured as: pre-Diabetic
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so, the metabolism in your body
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needs sleep to function properly
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and not just the metabolism
affecting insulin resistance,
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there's couple of hormones
that control our appetite
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and how much food we eat.
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Ghrelin and Leptin...
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Ghrelin is an enzyme...
not an enzyme... a hormone
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that is released
from your stomach
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and when your stomach is empty
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and ready to take another meal,
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you start putting out Ghrelin.
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Ghrelin says to
the rest of the body,
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"Hey, it's time to
eat... we're empty...
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we can take another meal here. "
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Leptin has sort of
the opposite effect,
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Leptin is
released by your fat cells
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and if you've got a
lot of fat cells built up,
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you're going to
put out more Leptin
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and Leptin goes and tells the
Appetite Center in the brain,
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it says, "Hey, we've got
a lot of food stored here,
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you really don't
need to eat right now... "
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but with sleep
deprivation, Ghrelin goes up...
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"Hey, it's time to
eat... stomach's empty... "
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and Leptin goes down...
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it quits saying, "Hey,
we have got plenty of food,
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we... "
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and so the brain says,
"Hey, well, we need food
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and the stomach's empty,
I think we're hungry... "
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and it puts out
those hunger signs
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and we move on down
that road to obesity
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affecting so many
people here in this country
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and with a lot of
serious health consequences
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associated with obesity there.
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Sleep deprivation contributes to
all major psychiatric conditions
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including anxiety,
depression and suicide.
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If you're not
getting enough sleep,
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you're pushing your
brain towards more anxiety...
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more depression
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and it meets a lot of the other
psychiatric conditions as well
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are pushed over the
edge with sleep deprivation
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and, of course,
sleep-deprived driving...
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driving home
after a night shift...
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sleep deprived can be the
same as driving on alcohol.
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Your reflexes...
your response time...
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everything is off...
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you can get these... it's like
the brain wants to sleep so bad,
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it starts getting
this little micro-sleeps...
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in other words,
you're trying to stay awake
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and yet the brain
kind of shuts off...
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and you... "Give me
my five minutes... "
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and you keep doing
that trying to stay awake...
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responsible for a
large amount of the...
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particularly,
single-vehicle accidents
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but many of the
multi-vehicle accidents as well
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can be traced back to a sleep-
deprivation individual there.
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Pause...
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The shorter your sleep
the shorter your life span...
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the two go together...
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longevity and adequate sleep
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are definitely paired together
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for it is said, "I'll
sleep when I'm dead. "
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If you accept that philosophy,
you're going to find that
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you're going to be dead sooner.
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You're going to
have a shorter life span
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and that shorter life span
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is going to have a lot
more misery, discomfort
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and illness of
various types in it.
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So, for a longer lifespan
and a healthier lifespan,
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get your sleep now
while you're still alive.
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The elastic band
of sleep deprivation
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can stretch only so
far before it snaps.
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Pause...
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Human beings
are the only species
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that deliberately
deprive themselves of sleep
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without any legitimate gain.
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Depriving yourself of sleep
is only going to put you behind
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or sputter out.
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There's a sleep-loss epidemic
throughout the industrialized
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nations...
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World Health
Organization has declared
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a sleep-loss epidemic.
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United States...
UK... Western Europe...
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Japan... South Korea...
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all of these countries...
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the majority of the
nation is running on less sleep
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than they really need
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and they're suffering
all of these consequences
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they talk about here...
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really, metabolic problems
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and psychiatric
problems... mental disease...
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all of those are increased and
enhanced with sleep deprivation.
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Pause...
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So, what is sleep?
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Pause...
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You know, we spend
all this time sleeping,
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what happens when we sleep?
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We are not unconscious...
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we're actually carrying on a
lot of very important activities
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in the brain...
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the brain is active
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but it's active in
a very different way
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carrying on very
different functions
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and you're not awake.
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Consciousness is a condition of
the brain in a non-sleep state
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and it depends on
eight hours of sleep a day
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to be able to function
optimally in that time there.
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One of the first questions
I was supposed to look at is:
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How do we know
when to go to sleep?
00:12:07.96\00:12:11.19
How does the body decide when
to sleep and when to wake up?
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We have a clock built in there
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and let's take a
look at the clock here...
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pause...
00:12:22.80\00:12:26.51
here in the... right over here
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in the very center here...
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you see that
little green spot there?
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Suprachiasmatic nucleous...
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it's a little
cluster of cells...
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there is a large
picture of it here...
00:12:40.36\00:12:43.73
down here at the base in
the center of the brain...
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or even expanded
picture of that here
00:12:45.99\00:12:48.43
of the different kinds of cells
that are clustered in there
00:12:48.46\00:12:52.43
and, of course, those cells have
axons and dendrites extend out
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to all kinds of other centers
and are connected to everything.
00:12:56.10\00:12:59.64
But, you know, in many computers
and electronic devices,
00:12:59.67\00:13:04.81
we have little
clocks built into them.
00:13:04.85\00:13:06.58
Well, your
brain is the same way,
00:13:06.61\00:13:08.52
it's got a clock
built in there...
00:13:08.58\00:13:10.45
we call it a circadian clock.
00:13:10.49\00:13:12.75
Circadian means
"circa" approximately or about
00:13:12.79\00:13:18.13
and "dia... " day...
00:13:18.16\00:13:20.40
so, Circadian...
days... about a day...
00:13:20.46\00:13:23.47
so this is a 24-hour clock,
00:13:23.50\00:13:25.70
there's specialized
proteins in there that build up
00:13:25.73\00:13:28.77
and build down
00:13:28.80\00:13:30.14
and the re-balance of
this oscillating thing...
00:13:30.17\00:13:32.74
positive and
negative feedback...
00:13:32.77\00:13:34.71
and it builds
up and goes down...
00:13:34.74\00:13:36.61
goes up... and it
oscillates in a 24-hour cycle
00:13:36.64\00:13:40.62
and what controls
when and how that is?
00:13:40.68\00:13:44.79
It's a daylight clock...
00:13:44.85\00:13:47.36
it's connected to your eye.
00:13:47.39\00:13:49.86
Now, most of us
are familiar with
00:13:49.89\00:13:55.06
the eye
00:13:55.13\00:13:57.23
and the light
comes in through the lens
00:13:57.27\00:14:00.00
it shines on the back...
we have the Retina there...
00:14:00.04\00:14:02.54
and here's an
expanded picture...
00:14:02.57\00:14:05.24
if you take just a
little piece of this Retina
00:14:05.27\00:14:08.18
and expand it here,
the light comes in this way
00:14:08.21\00:14:11.11
and right at
the base right here,
00:14:11.15\00:14:12.88
there's kind of a
reflective layer here
00:14:12.91\00:14:14.65
to kind of reflect back
as much light as possible
00:14:14.68\00:14:17.55
from the outer surface here
00:14:17.59\00:14:19.39
and these cells here
are the rods and the cones
00:14:19.45\00:14:22.52
responsible for real
dim black-and-white vision
00:14:22.56\00:14:25.66
as well as more
brighter daylight color vision
00:14:25.69\00:14:28.76
with the cones here
00:14:28.83\00:14:30.17
and usually when we think about
00:14:30.20\00:14:32.53
light-sensing
cells in the brain,
00:14:32.57\00:14:34.90
these are the cells
that sense the visual images
00:14:34.94\00:14:38.91
that are focused on the
Retina by the lens of your eye
00:14:38.94\00:14:43.45
and the message as they send
00:14:43.48\00:14:45.58
will go clear to the
very back of your brain
00:14:45.61\00:14:47.58
and that's where you will see
whatever it is you're looking at
00:14:47.62\00:14:50.95
but these are not the
only light-sensitive cells
00:14:50.99\00:14:54.46
in your brain, the
rods and the cones...
00:14:54.49\00:14:56.22
there is a third type
of light sensor in your eye
00:14:56.26\00:14:59.89
in addition to
the rods and the cones
00:14:59.96\00:15:01.86
and that... RGC cells right
up here called ganglion cells.
00:15:01.90\00:15:05.77
They're very different
and the information they send
00:15:05.83\00:15:11.41
goes out to neurons
00:15:11.44\00:15:12.77
and they do not connect back
to the back part of your brain
00:15:12.81\00:15:15.64
and you don't see images
or pictures with these cells.
00:15:15.71\00:15:21.52
Instead, these cells
send their signals of light
00:15:21.55\00:15:28.09
back to this super
chiasmic nucleus here.
00:15:28.12\00:15:32.69
Pause...
00:15:32.73\00:15:35.20
Here is a picture... here's
our super cosmic nucleus here,
00:15:35.23\00:15:40.44
a little clock and
sunlight comes in here
00:15:40.47\00:15:44.47
when we wake up
and open our eyes
00:15:44.51\00:15:47.38
and it's daylight
00:15:47.41\00:15:48.91
and it says,
"Hey, it's daylight... "
00:15:48.94\00:15:50.28
and so, the cell starts
going into its daylight cycle...
00:15:50.31\00:15:53.05
and it builds up
higher and higher and higher
00:15:53.11\00:15:55.55
stronger till
the middle of the day
00:15:55.58\00:15:56.92
and then as the day
wanes and light dims
00:15:56.95\00:16:00.22
and we move towards night,
00:16:00.26\00:16:01.62
this light's not coming
in here... it's cooled down
00:16:01.66\00:16:04.63
and it knows that it's off here
00:16:04.66\00:16:06.66
and it keeps in
this daily cycle here
00:16:06.70\00:16:09.00
and it's our daily experience
of day time... of sunlight
00:16:09.03\00:16:13.90
that keeps the clock
running so our brain knows
00:16:13.94\00:16:17.91
it's day time or night time
00:16:17.97\00:16:20.44
and we were designed to
be awake in the day time
00:16:20.48\00:16:23.45
and to be asleep at night time.
00:16:23.48\00:16:25.68
Now, this little center...
00:16:25.71\00:16:28.28
remember these are
little neurons here
00:16:28.32\00:16:29.88
and they got their messages
00:16:29.92\00:16:32.22
from the little
light-sensor cells here
00:16:32.25\00:16:34.06
which synapsed here...
00:16:34.09\00:16:35.66
gave them the
messages of daylight or not
00:16:35.69\00:16:38.26
and it went through
its daily clock cycle
00:16:38.29\00:16:40.86
and it's sending
out a continuous message
00:16:40.90\00:16:43.43
about sort of where we
are in the clock cycle here
00:16:43.47\00:16:45.93
electronically.
00:16:45.97\00:16:47.54
In other words,
little electrical impulses
00:16:47.57\00:16:49.97
are coming out
00:16:50.01\00:16:51.34
and they're going
down to different...
00:16:51.37\00:16:52.71
several different
centers in the brain here
00:16:52.74\00:16:54.58
as well as some down and
even in the brain stem here
00:16:54.61\00:16:57.81
they go down to here
00:16:57.85\00:16:59.18
and down in your neck
there's some centers there
00:16:59.21\00:17:01.98
and then they come
back up to the Pineal gland
00:17:02.02\00:17:05.89
and the Pineal gland is
what is going to show us
00:17:05.92\00:17:10.59
what... is going to show
everything else in the body
00:17:10.63\00:17:15.23
what time it is
00:17:15.26\00:17:16.83
and when it should be doing
what it's supposed to be doing.
00:17:16.87\00:17:19.70
Pause...
00:17:19.73\00:17:23.10
Here's a sort of a
little expanded picture.
00:17:23.14\00:17:24.97
Over here you can see these
are the Ganglion cells here
00:17:25.01\00:17:29.34
and these little
Ganglion cells here
00:17:29.38\00:17:32.98
are the ones that are sending
their messages back here.
00:17:33.01\00:17:35.75
Here's our little clock
00:17:35.78\00:17:37.69
and the clock is
sending messages out here
00:17:37.72\00:17:42.56
which is going way down here
00:17:42.59\00:17:45.09
up to some other centers
back up to the Pineal gland
00:17:45.13\00:17:48.00
which is going to
release Melatonin into the blood
00:17:48.03\00:17:50.87
to go to the rest of the body.
00:17:50.90\00:17:52.23
The Ganglion cells are also
sending some messages up here
00:17:52.27\00:17:56.77
to some other centers...
00:17:56.81\00:17:58.14
this particular reflex-pass-ways
and all these little things
00:17:58.17\00:18:01.84
sends a message back to the
eye... to the Iris of your eye
00:18:01.88\00:18:05.71
that opens and closes...
00:18:05.75\00:18:07.68
to control the
amount of light going in.
00:18:07.72\00:18:10.19
You shine a bright
light in somebody's eye,
00:18:10.22\00:18:11.89
what happens?
00:18:11.92\00:18:13.42
The pupil constricts down.
00:18:13.46\00:18:15.19
You take the bright
light away... it opens back up.
00:18:15.22\00:18:19.03
These are the little centers
that are controlling that
00:18:19.06\00:18:22.83
and they know because
of the Ganglion cells...
00:18:22.86\00:18:26.43
not the rods and cones...
00:18:26.47\00:18:27.80
so the Ganglion cells are
controlling that little reflex
00:18:27.84\00:18:30.04
but the one we're
interested in right now
00:18:30.11\00:18:32.87
is... that's
what's setting your clock.
00:18:32.91\00:18:35.61
So the clock knows when to
be running the daylight cycle
00:18:35.64\00:18:39.01
and it's sending the message
down here to the Pineal gland
00:18:39.05\00:18:42.42
and the Pineal gland is
going to release Melatonin.
00:18:42.45\00:18:45.89
Melatonin is a hormone.
00:18:45.92\00:18:48.22
Hormones are molecules
that control other cells
00:18:48.26\00:18:52.56
and in this case,
Melatonin is going to control
00:18:52.59\00:18:56.43
all of the other glands
and structures in the body
00:18:56.46\00:18:59.63
that need to be
running on a Circadian rhythm.
00:18:59.70\00:19:02.84
You know, it's kind of like,
00:19:02.87\00:19:05.57
if you think of all the
different organs of your body
00:19:05.61\00:19:08.18
as different
instruments in an orchestra,
00:19:08.21\00:19:12.11
now, if everybody put
ear plugs in their ears
00:19:12.18\00:19:15.98
and just looked at their music
and started playing a song,
00:19:16.02\00:19:20.12
after a while... some would
be playing a little faster,
00:19:20.16\00:19:23.99
some a little slower
00:19:24.03\00:19:25.36
and pretty soon
they'd be all out of sync
00:19:25.39\00:19:27.43
and that would make
terrible disharmony.
00:19:27.46\00:19:29.53
If you really
want to sound good,
00:19:29.56\00:19:31.83
what did all the
musicians need to do?
00:19:31.87\00:19:34.24
They need to look at the
Conductor who is doing the beat
00:19:34.27\00:19:39.21
and showing them when to come
00:19:39.24\00:19:41.11
and keeping them
all on the same beat
00:19:41.14\00:19:43.01
so they're all going together
at exactly the right time.
00:19:43.04\00:19:45.81
Melatonin is the
conductor waving that baton
00:19:45.85\00:19:51.25
and telling every
organ when to do its job.
00:19:51.32\00:19:56.69
It's like... if
you think about it...
00:19:56.73\00:20:00.46
the different glands
put out their hormones
00:20:00.50\00:20:04.77
at different times
00:20:04.80\00:20:06.13
and they know from
the Melatonin level
00:20:06.17\00:20:08.77
when it's time for
them to do their job.
00:20:08.80\00:20:11.31
Now, some may come
at a different time
00:20:11.34\00:20:13.58
just as different
instruments may play
00:20:13.64\00:20:15.84
in different parts and pieces
00:20:15.88\00:20:17.25
but they're all
watching the conductor
00:20:17.28\00:20:19.41
and they know when
to come in on their note
00:20:19.48\00:20:22.05
and play their part
based on how the conductor
00:20:22.08\00:20:24.62
is sending out that signal.
00:20:24.65\00:20:26.15
Pause...
00:20:26.19\00:20:29.42
This picture... you
don't want to memorize this,
00:20:29.46\00:20:31.73
I just threw this up so
you could get a little bit
00:20:31.76\00:20:34.03
of an idea of the complexity
00:20:34.06\00:20:36.83
of the various Neurotransmitters
that are used by the neurons
00:20:36.87\00:20:41.57
to communicate to
all of these centers
00:20:41.60\00:20:43.51
and eventually
to the Pineal gland
00:20:43.54\00:20:45.37
and if you'll notice
here how many of these Centers
00:20:45.41\00:20:49.98
could be related to the
action of various drugs,
00:20:50.01\00:20:54.52
in other words, we use
different medications or drugs
00:20:54.55\00:20:57.32
because they have
a biological effect.
00:20:57.35\00:20:59.39
In other words,
they'll go to... like...
00:20:59.42\00:21:01.96
here you have
Gamma aminobutyric acid
00:21:01.99\00:21:04.49
used as a
neurotransmitter here... here...
00:21:04.53\00:21:07.33
over here... over here...
00:21:07.36\00:21:10.03
and we use all
these places over here...
00:21:10.07\00:21:11.73
that particular receptor is
affected by the Benzodiazepines,
00:21:11.77\00:21:18.27
Ativan, Valium...
those types of drugs
00:21:18.31\00:21:21.44
and so, any time
you take one of those,
00:21:21.48\00:21:24.25
besides what it's
doing over your mid-lower
00:21:24.28\00:21:26.98
or other parts of the brain,
00:21:27.02\00:21:28.65
it's also affecting these areas
00:21:28.68\00:21:30.25
and the same with this
Opioid receptors here...
00:21:30.29\00:21:33.89
there's a hydroxytryptophan...
00:21:33.92\00:21:36.52
there is all these different...
acetylcholine down here...
00:21:36.56\00:21:41.36
norepinephrine here...
00:21:41.40\00:21:42.86
all of these different things...
00:21:42.93\00:21:44.67
different drugs are affecting
all of those in various ways
00:21:44.73\00:21:48.27
and I want you to get a picture
of the complexity of the brain,
00:21:48.30\00:21:52.51
the delicateness of all
of these little circuits
00:21:52.54\00:21:55.54
that have to work just right
for everything to go right.
00:21:55.58\00:21:58.81
When you take a drug, it
doesn't just go to the one place
00:21:58.85\00:22:02.08
where, "Oh, I'm taking this
00:22:02.12\00:22:03.45
so that it will
make me feel better here
00:22:03.49\00:22:05.19
or I'm taking this for this... "
00:22:05.25\00:22:06.59
it's also going to
100s of different places
00:22:06.62\00:22:09.79
and messing up how
they're working as well.
00:22:09.82\00:22:13.19
The ideal is that the
brain can run clear and clean
00:22:13.23\00:22:19.00
as God designed it...
00:22:19.03\00:22:20.60
fresh... without interference...
outside interference...
00:22:20.64\00:22:25.97
He designed just
the right balance
00:22:26.01\00:22:27.61
of everything going on there.
00:22:27.64\00:22:29.84
Sometimes, in emergency cases,
00:22:29.88\00:22:31.98
we have to use
certain medications
00:22:32.01\00:22:34.28
to override some
terrible problem in there
00:22:34.32\00:22:37.12
but that's why all
medications have side effects...
00:22:37.15\00:22:39.85
that's because they not only
do what you want them to do,
00:22:39.89\00:22:43.16
they also are going to
start jamming up the network
00:22:43.19\00:22:46.39
in all the other places
00:22:46.43\00:22:47.76
so, the ideal is to come
back to the perfect diet...
00:22:47.80\00:22:52.37
perfect night's
sleep every night...
00:22:52.40\00:22:55.84
so important for all
these neurons especially...
00:22:55.90\00:22:59.37
and in those...
that situation...
00:22:59.41\00:23:01.61
with proper
diet... without toxins,
00:23:01.64\00:23:04.11
without junk food
00:23:04.15\00:23:05.48
and without drugs...
00:23:05.51\00:23:06.85
we're going to get the
best functioning of the brain...
00:23:06.88\00:23:11.49
the best mind and synapses
that God can communicate with.
00:23:11.55\00:23:16.22
Here's a picture of
Melatonin release...
00:23:16.26\00:23:20.70
remember the release
of Melatonin here is...
00:23:20.73\00:23:25.10
you know, from the Pineal
gland is coming out because
00:23:25.13\00:23:28.57
the lights send it through
all these electrical signals...
00:23:28.60\00:23:31.34
through all these little
synapses with their chemicals
00:23:31.37\00:23:34.08
and so it knows when
to put the Melatonin out.
00:23:34.11\00:23:36.75
Now, if we measured the
Melatonin in the blood...
00:23:36.78\00:23:39.38
so, now we've got a
hormone in the blood...
00:23:39.41\00:23:41.65
the hormone is Melatonin...
here's what it looks like...
00:23:41.68\00:23:44.59
it's made out of
hydroxytryptophan.
00:23:44.62\00:23:47.36
Here is your
level... going along here...
00:23:47.42\00:23:51.19
Melatonin level in your body
is close to zero during the day,
00:23:51.23\00:23:55.26
there's no Melatonin
circulating in your blood
00:23:55.30\00:23:57.57
but here in the evening,
00:23:57.60\00:23:59.30
here we've got
about 8 o'clock at night,
00:23:59.33\00:24:01.14
it's dark... it's now it says...
"Oh, it's night time... "
00:24:01.17\00:24:05.61
and Melatonin levels
shoot up and peak up here
00:24:05.67\00:24:09.04
till we get
really high levels here
00:24:09.08\00:24:11.51
by the middle of the night
00:24:11.55\00:24:13.18
and then, they drop
off precipitously...
00:24:13.21\00:24:15.48
in the morning, we're
back down to zero there.
00:24:15.52\00:24:20.12
Pause...
00:24:20.16\00:24:21.56
and it continues
"zero" all day long
00:24:21.59\00:24:25.59
and it's this
pulsing piece at night time
00:24:25.63\00:24:28.63
that helps you to bring
on the process of sleep...
00:24:28.66\00:24:32.20
it's sort of like the...
00:24:32.23\00:24:33.70
it's not what
makes your sleep...
00:24:33.74\00:24:36.57
it's what tells
you when to sleep
00:24:36.60\00:24:39.37
and there's Melatonin
receptors in the brain
00:24:39.44\00:24:42.44
and Melatonin is a key
that can push you down that.
00:24:42.48\00:24:45.85
It's sort of like the...
00:24:45.88\00:24:47.45
you got a bunch
of runners here...
00:24:47.52\00:24:49.28
ready to run a race
00:24:49.35\00:24:51.72
and you've got
somebody on the starting line
00:24:51.75\00:24:53.39
with a starting gun... he says,
00:24:53.46\00:24:54.82
"On your mark... get
set... go... " boom...
00:24:54.86\00:24:57.69
well, Melatonin is
that firing of that gun...
00:24:57.73\00:25:00.56
getting everybody up
moving there on time.
00:25:00.60\00:25:04.00
Pause...
00:25:04.03\00:25:07.87
Here you can see
Melatonin controlling
00:25:07.90\00:25:09.80
the output of Cortisol
from the adrenal cortex.
00:25:09.84\00:25:13.17
You notice here as the...
00:25:13.21\00:25:18.95
here the red is the
Melatonin peaking at night...
00:25:18.98\00:25:22.12
notice Cortisol is down there
00:25:22.18\00:25:24.42
but it's the drop in Melatonin
00:25:24.45\00:25:26.59
lets the adrenal gland know,
00:25:26.62\00:25:28.66
"Oh, it's time to
put out Cortisol... "
00:25:28.72\00:25:30.33
so, as this drops... it
starts pouring out Cortisol,
00:25:30.36\00:25:33.36
Cortisol is going to peak here
in the middle of the morning
00:25:33.40\00:25:37.27
and Cortisol gives
you that kind of good
00:25:37.30\00:25:40.67
"top of the morning" feeling...
00:25:40.70\00:25:42.17
everything is
zooming along great now...
00:25:42.20\00:25:44.07
it was Melatonin that put
it there at the right time.
00:25:44.11\00:25:49.21
All of the other
hormones in the body
00:25:49.24\00:25:51.68
run on Circadian... thyroid
hormone has a Circadian...
00:25:51.71\00:25:55.55
here's your body temperature.
00:25:55.58\00:25:57.15
Notice here as your Melatonin
in green there peaks at night,
00:25:57.19\00:26:01.99
the body temperature drops,
00:26:02.02\00:26:04.23
it actually goes
a few degrees cooler
00:26:04.26\00:26:05.99
and that cooling of the
body actually induces sleep...
00:26:06.03\00:26:09.70
it helps... one of the
things that helps with sleep.
00:26:09.73\00:26:13.37
You sleep better in a cool room.
00:26:13.40\00:26:15.30
You'll sleep better
if you're not overheated
00:26:15.34\00:26:18.21
and the Melatonin is helping
to push your body into that
00:26:18.24\00:26:22.14
by dropping the
body's temperature
00:26:22.18\00:26:24.21
just a little bit there.
00:26:24.25\00:26:26.45
Melatonin changes with age.
00:26:26.48\00:26:28.58
That big high peak...
that black line up there
00:26:28.62\00:26:31.99
is children.
00:26:32.02\00:26:33.36
Children have the
highest Melatonin levels
00:26:33.39\00:26:36.46
and how much do children sleep?
00:26:36.49\00:26:39.93
A lot... and
they need that sleep.
00:26:40.00\00:26:42.36
You know that phrase,
"Sleep like a baby... "
00:26:42.40\00:26:44.40
that's Melatonin.
00:26:44.43\00:26:46.00
That's telling the body,
"Hey, you need to sleep...
00:26:46.03\00:26:48.60
let's turn on
sleep and keeps going. "
00:26:48.64\00:26:51.07
At Adolescence and
puberty, there is a drop in that
00:26:51.11\00:26:55.74
and now the
"Melatonin peaks" every night
00:26:55.81\00:26:58.51
are not quite as high
00:26:58.58\00:27:00.55
and that helps turn
the clock on puberty
00:27:00.58\00:27:03.79
and actually tell the
body, "Now is the time... "
00:27:03.85\00:27:06.02
it's part of that change there,
00:27:06.05\00:27:08.09
but it also starts
running at that level
00:27:08.12\00:27:10.66
and that's the ideal level of
probably for the peak or ideal
00:27:10.73\00:27:16.26
or the body is
running at its greatest
00:27:16.30\00:27:18.93
at those levels right there.
00:27:18.97\00:27:20.30
But as time passes, we
get to the 40s and 50s...
00:27:20.34\00:27:24.67
the level gets lower.
00:27:24.71\00:27:26.71
Now, we might start having...
not sleeping as well...
00:27:26.74\00:27:29.98
not as easy to fall asleep...
00:27:30.01\00:27:31.85
and 50s and 60s
levels are lower...
00:27:31.88\00:27:35.52
past 65... I mean
we're way down there
00:27:35.55\00:27:39.15
barely peaking out and...
00:27:39.19\00:27:40.69
in other words,
with age, we deteriorate
00:27:40.76\00:27:43.02
the amount of Melatonin
coming out is less and less.
00:27:43.06\00:27:47.50
This is why we often give
a recommendation with age...
00:27:47.53\00:27:51.90
if there is difficulty sleeping,
supplementing with Melatonin
00:27:51.93\00:27:56.40
at bedtime can
actually be an excellent...
00:27:56.47\00:28:00.01
to restore that Melatonin surge
00:28:00.04\00:28:02.54
back up to its
useful levels there
00:28:02.58\00:28:05.01
and so, many people
recommend Melatonin at bedtime.
00:28:05.05\00:28:09.68
It's not a drug per se...
00:28:09.72\00:28:12.59
you're just
restoring to the body
00:28:12.62\00:28:14.62
what God always
designed to be in there
00:28:14.66\00:28:16.86
and helping to push this
00:28:16.89\00:28:18.69
process along and to its
right functioning status there.
00:28:18.73\00:28:27.24
Pause...
00:28:27.27\00:28:29.70
Here's another interesting
phenomenon in Melatonin.
00:28:29.74\00:28:32.71
In the gray there,
00:28:32.74\00:28:34.78
you'll see the normal
Melatonin's peak at night here
00:28:34.84\00:28:39.31
this nice big peak here...
00:28:39.35\00:28:41.32
pause...
00:28:41.35\00:28:42.72
but now see this
orange line here...
00:28:42.75\00:28:44.82
this kind of
dotted orange line...
00:28:44.85\00:28:46.89
adolescence... the teenagers...
high-school-age kids...
00:28:46.92\00:28:51.69
their Melatonin level
shifts forward couple of hours
00:28:51.73\00:28:56.67
and what happens is,
00:28:56.70\00:28:58.67
ever see why they don't
want to go to bed at night?
00:28:58.70\00:29:02.07
The Melatonin
hasn't come up yet...
00:29:02.10\00:29:04.47
they're not sleepy yet
00:29:04.51\00:29:06.41
and they want to
stay up late at night.
00:29:06.44\00:29:08.44
The problem isn't on that end,
00:29:08.48\00:29:11.91
the problem seems
to be on the other end
00:29:11.95\00:29:13.92
because now... when
the rest of the adult world
00:29:13.95\00:29:17.95
has them scheduled to get up
and get going in the morning,
00:29:17.99\00:29:21.26
they're in the middle of
their deep Melatonin-sleep cycle
00:29:21.29\00:29:24.36
and they need that sleep
00:29:24.39\00:29:25.73
and what we end up doing here
00:29:25.76\00:29:28.46
is cutting off
the sleep back here
00:29:28.50\00:29:32.47
because the alarm clock goes
off... it's time to start school
00:29:32.50\00:29:35.54
and so, we're
actually cutting off this...
00:29:35.57\00:29:37.97
all of this sleep that
would be going on out here
00:29:38.01\00:29:41.94
because we didn't
go to bed till then
00:29:41.98\00:29:43.51
and now we cut it off here...
00:29:43.55\00:29:44.88
we've really
shortened the night's sleep
00:29:44.91\00:29:46.72
and we've cut off that late...
you know, that morning sleep
00:29:46.75\00:29:51.29
which is where your REM
sleep is so important for the
00:29:51.32\00:29:54.39
many parts of
learning and functioning...
00:29:54.42\00:29:57.06
ideally, we would start high
school at 9 or 10 in the morning
00:29:57.09\00:30:01.80
and then extend it later in the
afternoon to get in the hours
00:30:01.83\00:30:06.47
but that would be
the ideal for learning.
00:30:06.50\00:30:10.51
There have been school
systems that have tried that
00:30:10.54\00:30:13.61
with excellent results.
00:30:13.64\00:30:15.58
One of them... everybody's
grade point went up...
00:30:15.61\00:30:18.75
most students went
up above one letter...
00:30:18.78\00:30:21.68
you know, if
they were a C student,
00:30:21.72\00:30:23.35
they became a B student...
00:30:23.39\00:30:24.72
if they were a B student,
they became an A student.
00:30:24.75\00:30:26.55
ACT and SAT scores
also went up significantly
00:30:26.59\00:30:31.36
with switching
to this later cycle
00:30:31.39\00:30:35.46
because now they were
learning in the right place.
00:30:35.50\00:30:39.03
The brain is
essential for learning
00:30:39.07\00:30:42.97
and the sleep is
essential for the brain.
00:30:43.00\00:30:47.48
So, let's take a look
at what really is sleep...
00:30:47.51\00:30:49.61
what is going on there.
00:30:49.64\00:30:51.48
Here is a diagram of
what happens in sleep.
00:30:51.51\00:30:56.12
So, we have
here levels of sleep.
00:30:56.15\00:30:58.65
At the top level
right here is being awake.
00:30:58.72\00:31:02.39
Now, as we move down in here,
the very first level here...
00:31:02.42\00:31:06.66
this next level just below
wake is what we call: REM Sleep.
00:31:06.70\00:31:10.93
REM stands for:
Rapid Eye Movement
00:31:10.97\00:31:14.07
and it was observed that
00:31:14.10\00:31:16.60
at certain times
when people are sleeping,
00:31:16.67\00:31:19.34
their eyelids are closed... but
underneath their closed eyelids,
00:31:19.37\00:31:22.71
their eyeballs are
darting back and forth
00:31:22.74\00:31:24.98
and around and
all over the place
00:31:25.01\00:31:26.38
it's just this jerking
random movements of the eyes
00:31:26.41\00:31:30.49
and so they call
it: Rapid Eye Movement.
00:31:30.52\00:31:33.25
They don't know
exactly why the eyes do that
00:31:33.29\00:31:35.99
during this particular sleep
00:31:36.02\00:31:37.49
but that's a
normal physiological thing
00:31:37.53\00:31:40.20
to have this rapid eye movement
00:31:40.23\00:31:42.06
in this one
particular phase of sleep.
00:31:42.10\00:31:44.60
In the other parts of sleep,
the eyes are resting quietly
00:31:44.63\00:31:50.01
and not doing this
rapid eye movement,
00:31:50.07\00:31:51.94
so, we call
those: Non-REM Sleep.
00:31:51.97\00:31:54.48
So, we have REM
Sleep and Non-REM Sleep
00:31:54.51\00:31:59.11
and the REM Sleep is
divided into stages...
00:31:59.15\00:32:03.72
Stage one...
two... three... four...
00:32:03.79\00:32:05.39
as we go deeper and deeper
into very deep sleep here.
00:32:05.45\00:32:08.42
So, when we start off the night,
00:32:08.46\00:32:10.69
we go through
these cycles of sleep...
00:32:10.73\00:32:12.59
they're about an
hour and a half...
00:32:12.63\00:32:14.43
about 90 minutes
will go through a cycle
00:32:14.46\00:32:16.87
and then come back up
00:32:16.90\00:32:18.30
and then another
90-minute cycle and come back up
00:32:18.33\00:32:21.00
another 90-minute
cycle and on through there
00:32:21.04\00:32:23.64
we'll do this approximately
90-minute cycles here
00:32:23.67\00:32:26.47
through the night till
we've had gotten our eight hours
00:32:26.54\00:32:29.58
and it's time to
wake up and stay awake.
00:32:29.61\00:32:31.91
There can be some
brief awakenings...
00:32:31.95\00:32:34.22
these really brief ones...
00:32:34.28\00:32:36.42
you probably don't
remember in the morning
00:32:36.45\00:32:38.39
and didn't realize you woke up
00:32:38.42\00:32:39.85
and thought you
slept the whole night
00:32:39.89\00:32:41.22
but there was actually...
00:32:41.26\00:32:42.62
if we measure the
brain waves there...
00:32:42.66\00:32:43.99
there's this little peak here.
00:32:44.03\00:32:45.59
So, what is the brain doing
during these various stages?
00:32:45.63\00:32:49.56
We can hook up wires and
measure the electrical activity
00:32:49.60\00:32:53.50
and something we call an EEG...
00:32:53.54\00:32:57.07
here is a picture here... on
the top here, we can see here
00:32:57.11\00:33:01.64
this is the EEG of a
normal awake brain...
00:33:01.68\00:33:06.55
they're small... low voltage
00:33:06.58\00:33:08.65
and they're
random all over the place
00:33:08.68\00:33:10.82
not in particular frequencies...
00:33:10.85\00:33:12.45
they're just darting everywhere
00:33:12.49\00:33:14.06
and that is the normal,
conscious electrical activity
00:33:14.09\00:33:17.69
as you think "thoughts"
00:33:17.73\00:33:19.09
this neuron is sending
a message here and there
00:33:19.13\00:33:21.06
and you're getting
sensory input in...
00:33:21.10\00:33:23.60
you're doing motor things,
00:33:23.63\00:33:24.97
you're thinking about things
00:33:25.00\00:33:26.33
and there's all of these
different little electrical
00:33:26.37\00:33:27.90
activities just
bouncing all over the place
00:33:27.97\00:33:30.34
and this is what it looks like.
00:33:30.37\00:33:32.57
There is a place...
those are called: Beta waves.
00:33:32.61\00:33:36.71
There is a state
called: Alpha waves...
00:33:36.75\00:33:38.61
we find when someone's
very relaxed and meditative...
00:33:38.65\00:33:42.28
peaceful state of mind...
00:33:42.32\00:33:43.95
they're at the beach
watching the waves...
00:33:43.99\00:33:46.92
everything is happy
00:33:46.96\00:33:48.29
and they're not stressing
their mind over anything
00:33:48.32\00:33:50.19
and these Alpha
waves are very beneficial
00:33:50.23\00:33:53.06
but they're not sleep...
00:33:53.09\00:33:54.43
the person is conscious...
00:33:54.46\00:33:55.86
and able to think about things
00:33:55.93\00:33:57.47
and talk and
respond appropriately...
00:33:57.50\00:34:00.14
sense the environment...
00:34:00.17\00:34:01.50
enjoy the beauty of the scenery.
00:34:01.54\00:34:03.30
Here's what REM sleep
looks at... this highest level
00:34:03.34\00:34:07.41
and if you look at it,
one thing you'll notice is...
00:34:07.44\00:34:11.48
it looks almost
identical to the "awake state"
00:34:11.51\00:34:14.62
and really if
you're looking at the EEG,
00:34:14.65\00:34:17.95
you really can't tell the
difference between the awake
00:34:17.99\00:34:21.72
and the... the REM sleep.
00:34:21.76\00:34:25.56
This is where
dreaming takes place...
00:34:25.59\00:34:28.43
dreaming is that state...
00:34:28.46\00:34:30.80
very important for
organizing creativity
00:34:30.83\00:34:36.77
so you sort everything out...
get the new thoughts going
00:34:36.81\00:34:40.34
and during dreams,
you're sort of living through
00:34:40.38\00:34:43.51
these random pieces
being pulled from here to there
00:34:43.55\00:34:46.65
and connected in unusual ways
00:34:46.68\00:34:49.15
that you were never
connected before in your life
00:34:49.18\00:34:52.02
but it's just
one of those things
00:34:52.05\00:34:54.16
that happens
usually when you wake up
00:34:54.19\00:34:56.46
the dream that
REM sleep dream passes
00:34:56.49\00:34:58.66
but that's what the
electrical activity looks like
00:34:58.69\00:35:02.60
during REM sleep.
00:35:02.63\00:35:04.67
Now, as we move
into the non-REM sleep,
00:35:04.70\00:35:07.40
we get a much more regular...
00:35:07.44\00:35:10.04
Stage one: you see
it's a little bit...
00:35:10.07\00:35:12.01
much more regular,
00:35:12.07\00:35:13.41
it looks a little
bit like the REM sleep
00:35:13.44\00:35:14.98
but we're starting
to become more regular
00:35:15.01\00:35:16.78
and if you look at
the closing paradigm,
00:35:16.81\00:35:18.71
you can see that
this definitely moving...
00:35:18.75\00:35:20.62
well, they call
them Theta waves...
00:35:20.65\00:35:22.05
and as we go deeper into
there... these Theta waves,
00:35:22.08\00:35:25.25
we get these things
called: Sleep Spindles here.
00:35:25.29\00:35:28.39
It's like it goes: Bishhhht...
00:35:28.42\00:35:29.86
and every few
seconds... Bishhhht...
00:35:29.89\00:35:32.26
Bishhhht...
00:35:32.29\00:35:33.80
and we get these K waves
these little flumps in there...
00:35:33.83\00:35:36.23
fascinating activity
there what's going on...
00:35:36.26\00:35:40.07
it's actually
memories from the day
00:35:40.10\00:35:43.74
being stored in your
brain... it's fantastic.
00:35:43.77\00:35:47.51
As we go deeper down
here you get these Delta waves
00:35:47.54\00:35:51.48
really big slow wave activity
spreading through the brain.
00:35:51.51\00:35:56.52
They're not random things
going from here to there...
00:35:56.55\00:36:02.19
these Delta
waves... beautiful...
00:36:02.22\00:36:05.03
they start right
here in your frontal lobe
00:36:05.06\00:36:07.70
you know, where
your conscious thought
00:36:07.73\00:36:10.33
and everything is right here...
00:36:10.37\00:36:11.70
they start right
there... and shooooo...
00:36:11.73\00:36:13.70
they spread back
over the brain...
00:36:13.74\00:36:15.57
it's sort of like,
during the day and conscious...
00:36:15.60\00:36:18.84
there's random
things going everywhere...
00:36:18.87\00:36:20.58
but imagine yourself at the...
a large crowd and audience
00:36:20.61\00:36:25.58
at a football show
and they do a wave...
00:36:25.61\00:36:27.35
you know, one side people
stand up and raise their hands
00:36:27.38\00:36:30.72
and then sit down...
00:36:30.75\00:36:32.09
and the people next to them...
00:36:32.12\00:36:33.69
and as they go...
they just spread...
00:36:33.72\00:36:35.36
there's a wave of people
going all around the room...
00:36:35.39\00:36:37.46
makes a circle around
here and it goes again.
00:36:37.49\00:36:39.26
That's what this is.
00:36:39.29\00:36:41.03
Every neuron in the
brain is firing in sequence
00:36:41.06\00:36:44.13
from the front to the back.
00:36:44.17\00:36:45.83
It's not sending
their axons here...
00:36:45.87\00:36:47.20
they're each
firing electrolytes...
00:36:47.24\00:36:49.04
all they're trying
to get this high voltage
00:36:49.07\00:36:50.97
but slow wave
activity... fantastic...
00:36:51.01\00:36:55.18
so, this is what's taking place
00:36:55.21\00:36:58.51
during these
really deep cycles here...
00:36:58.55\00:37:01.92
these really deep
cycles that happen
00:37:01.95\00:37:05.25
first thing in the night...
00:37:05.29\00:37:06.62
so important for
restoring your body
00:37:06.65\00:37:08.86
and getting health
00:37:08.92\00:37:10.69
but there's also some
deep cleaning going on there.
00:37:10.73\00:37:15.13
Pause...
00:37:15.16\00:37:18.33
You know, during the day
your brain builds up toxins...
00:37:18.37\00:37:21.94
waste products...
metabolic by-products...
00:37:21.97\00:37:26.17
drugs might be there...
00:37:26.21\00:37:27.81
all kinds of stuff
builds up around there
00:37:27.84\00:37:30.01
and these neurons
can't function well
00:37:30.05\00:37:32.11
with all of that other
stuff contaminating them...
00:37:32.15\00:37:35.15
the various waste
products and everything.
00:37:35.18\00:37:36.75
We need a clean wash water
to flush and clean that all out
00:37:36.79\00:37:40.52
and it's the most
amazing thing that happens
00:37:40.56\00:37:43.69
as these Delta waves
start coming across the brain...
00:37:43.73\00:37:46.19
if you imagine your brain tissue
00:37:46.23\00:37:48.76
looking at... like
a picture of a city
00:37:48.80\00:37:51.07
and there's city block
with all of these streets
00:37:51.10\00:37:53.74
and avenues
crisscrossing back and forth
00:37:53.77\00:37:56.20
and there's a
river on each side here
00:37:56.24\00:37:58.51
one.. a river of
clean water over here
00:37:58.57\00:38:00.91
and one... the
drain river over here.
00:38:00.98\00:38:03.31
What happens during
this Delta-wave sleep?
00:38:03.35\00:38:06.41
If you could imagine at
night every building in the city
00:38:06.45\00:38:11.19
shrunk down to about
60% of its normal size...
00:38:11.22\00:38:14.76
that means all
the streets widened up
00:38:14.79\00:38:17.56
and suddenly you got these huge
wide spaces between everything
00:38:17.59\00:38:21.13
and clear clean
water... cerebral spinal fluid
00:38:21.16\00:38:25.27
pours out of clean water...
flushes through the brain
00:38:25.30\00:38:28.90
washing all of the
debris... the waste product...
00:38:28.94\00:38:32.51
the toxins... everything is
washed out into the other river
00:38:32.54\00:38:36.01
and washed off down and
out to the sea to get rid of it
00:38:36.04\00:38:39.41
and for this 90 minutes here
while you're in that deep cycle,
00:38:39.48\00:38:44.12
all of the brain has
just opened wide open
00:38:44.15\00:38:46.62
flushing this clear
cerebral spinal fluid...
00:38:46.65\00:38:49.06
just cleaning
the whole thing out
00:38:49.09\00:38:50.53
and then, very shortly, it
goes through another cycle.
00:38:50.56\00:38:54.73
You know, it expands back out
00:38:54.76\00:38:56.67
but then it does it
again... it shrinks down
00:38:56.70\00:38:58.93
and the water
flushes it through again...
00:38:58.97\00:39:01.17
we've got another
power wash here...
00:39:01.20\00:39:03.14
very, very important
to get those power washes
00:39:03.20\00:39:05.94
cleaning the brain.
00:39:05.97\00:39:08.18
You know, a little
thing to think about what's...
00:39:08.21\00:39:10.05
imagine the brain as an office
00:39:10.11\00:39:12.81
and in the office,
you've got this desk
00:39:12.85\00:39:15.02
and during the day
everything you thought and heard
00:39:15.05\00:39:18.05
and imagined came pouring in
00:39:18.09\00:39:20.02
and it all just kind of
piled up on your desk...
00:39:20.06\00:39:22.06
everything you
heard... everything you did...
00:39:22.09\00:39:24.06
it's just...
everything is there.
00:39:24.13\00:39:25.59
Important...
unimportant stuff...
00:39:25.63\00:39:26.96
everything is there...
00:39:27.00\00:39:28.93
at night, it's closing time...
00:39:28.96\00:39:31.13
time to go to sleep
00:39:31.17\00:39:32.50
and it's like you
pull down the shades...
00:39:32.53\00:39:34.67
put out the "Closed"
sign you become unconscious
00:39:34.70\00:39:37.84
but the cleaning crew
comes in, the Janitors...
00:39:37.87\00:39:40.98
and they do this deep cleaning,
00:39:41.01\00:39:42.78
washing...
cleaning... crevices...
00:39:42.81\00:39:44.35
everything in the office
00:39:44.41\00:39:45.75
but on your desk... you've
got important stuff among those
00:39:45.78\00:39:50.99
as you sort through the papers,
00:39:51.02\00:39:52.35
here's some
really important stuff...
00:39:52.39\00:39:53.72
maybe you were learning
to ride a bicycle that day
00:39:53.76\00:39:57.06
or maybe you were learning
to play a song on the piano...
00:39:57.09\00:39:59.43
all of that activity...
those motor activities
00:39:59.49\00:40:02.53
is important stuff
you want to save...
00:40:02.56\00:40:04.20
by-the-way, your frontal lobe
actually controls and sorts out
00:40:04.23\00:40:08.20
and knows what's
important and what's not
00:40:08.24\00:40:09.77
and if you... it's important...
you can actually save it
00:40:09.80\00:40:13.94
and these...
these bzzz... bzzzz...
00:40:13.98\00:40:20.75
these little sleep spindles...
00:40:20.82\00:40:22.15
that's actually passing
from your Hippocampus...
00:40:22.18\00:40:25.89
your short-term
memory up to your cortex
00:40:25.92\00:40:28.09
where you got to put in this
array of this complex cortex
00:40:28.12\00:40:33.19
that's doing
everything important for you
00:40:33.23\00:40:35.33
and remembering everything...
00:40:35.36\00:40:37.17
your long-term
storage... it's all saved there
00:40:37.20\00:40:40.70
and it's this
little bzzz... bzzz...
00:40:40.74\00:40:42.30
they can actually measure them
00:40:42.37\00:40:44.14
someone that's been working
hard on a piano or whatever...
00:40:44.17\00:40:47.38
it goes to those
parts of the brain
00:40:47.41\00:40:49.04
where you would
store that activity...
00:40:49.08\00:40:50.65
they can make sure
all this is going there
00:40:50.71\00:40:52.21
and if you had other types
of things... it's going there
00:40:52.25\00:40:55.08
and it goes to the right places
to save what you need there.
00:40:55.12\00:40:57.89
It's sort of like a
filing cabinet in the office,
00:40:57.92\00:41:00.26
you take all
the important things
00:41:00.29\00:41:01.62
and you're putting
them in the right folder
00:41:01.66\00:41:02.99
so you can find them again.
00:41:03.02\00:41:04.43
A person laying the...
00:41:04.46\00:41:05.79
they can take and
practice at the piano
00:41:05.83\00:41:07.66
over and over and over
00:41:07.70\00:41:09.03
and the piece still seems
like it's not quite right...
00:41:09.06\00:41:10.87
but they're doing
their best to practice it...
00:41:10.90\00:41:12.73
they go to sleep at night...
get a good sound sleep...
00:41:12.77\00:41:16.44
it all gets filed perfectly...
00:41:16.50\00:41:18.17
next morning they
go out to the piano
00:41:18.21\00:41:21.74
and suddenly now, it just flows.
00:41:21.78\00:41:23.75
Why? because they're not pulling
it from the short-term...
00:41:23.81\00:41:26.35
it's already stored in
the long coordinated memory...
00:41:26.38\00:41:29.52
the Cerebellum's
coordinating it...
00:41:29.58\00:41:31.45
everything's working good there
00:41:31.49\00:41:32.82
but it's not just important
to save the important stuff,
00:41:32.85\00:41:35.69
we've got to get rid
of the unimportant stuff.
00:41:35.72\00:41:40.36
I mean, you
probably... when you got into...
00:41:40.40\00:41:44.97
went into the
store or something,
00:41:45.00\00:41:47.07
you remember where you parked
your car out in the parking lot.
00:41:47.10\00:41:49.50
Well, that's important to
remember a few hours later
00:41:49.54\00:41:52.37
when you want to find your car,
00:41:52.41\00:41:53.78
but you don't need
to remember next year
00:41:53.81\00:41:57.11
where you parked it today.
00:41:57.15\00:41:58.48
That's unimportant information
and it's sort of like,
00:41:58.51\00:42:02.18
you store all of this
stuff on a flash drive
00:42:02.22\00:42:04.39
and the flash drive is full of
everything you've heard and seen
00:42:04.45\00:42:08.19
unimportant stuff...
00:42:08.22\00:42:09.56
what we need to do
for the next day...
00:42:09.59\00:42:11.69
you can only hold so
much on the flash drive
00:42:11.73\00:42:13.26
so, what do you do?
00:42:13.29\00:42:14.63
You go through and
delete it, you clean it out
00:42:14.66\00:42:16.56
and we find that up in the first
and-second-stage sleep here,
00:42:16.60\00:42:20.14
we're actually... go through
00:42:20.17\00:42:24.34
and we can
actually here... store...
00:42:24.37\00:42:27.71
we're actually
cleaning up the flash drive
00:42:27.74\00:42:29.94
here in the Hippocampus...
00:42:29.98\00:42:31.61
we're just cleaning
out the flash drive...
00:42:31.65\00:42:32.98
getting rid of all of the
unimportant stuff... deleting it
00:42:33.01\00:42:34.82
by now, we've got
the desk cleaned off...
00:42:34.85\00:42:37.02
we've saved the
important stuff and filed it...
00:42:37.05\00:42:38.92
we've deleted
the unimportant stuff
00:42:38.95\00:42:41.12
and now it's time for REM sleep.
00:42:41.16\00:42:43.32
Now is the time
for creativity...
00:42:43.36\00:42:45.46
your desk is clean...
the office is washed...
00:42:45.49\00:42:47.83
there's nothing to distract
00:42:47.86\00:42:49.20
and the brain can actually
start taking different things
00:42:49.23\00:42:52.63
and come up with
creative stuff...
00:42:52.67\00:42:55.40
all kinds of... the important...
00:42:55.44\00:42:58.14
the things that
make life valuable...
00:42:58.17\00:42:59.84
happen in this REM sleep.
00:42:59.87\00:43:01.68
Lot of people manage
sleep deprivation with Caffeine.
00:43:01.71\00:43:08.38
What is it really doing here?
00:43:08.42\00:43:11.25
In this graph right here,
00:43:11.29\00:43:14.06
we're looking at a
couple of things right here...
00:43:14.09\00:43:19.59
there is a substance in
your brain called: Adenosine.
00:43:19.63\00:43:25.13
Adenosine builds up...
starting in the morning
00:43:25.17\00:43:31.44
your Adenosine
level starts building up
00:43:31.47\00:43:33.51
and it builds up
through the day in the brain
00:43:33.54\00:43:36.41
and when the
Adenosine level is high,
00:43:36.44\00:43:38.71
you feel tired.
00:43:38.75\00:43:40.52
Tiredness is Adenosine
being built up in the brain
00:43:40.55\00:43:46.12
and the more tired you get...
00:43:46.15\00:43:48.76
is because you've got
the Adenosine built up...
00:43:48.79\00:43:52.56
that is the function of it there
00:43:52.59\00:43:56.83
and is it... there's special
receptors on all the cells,
00:43:56.87\00:44:00.57
they know
Adenosine is building up
00:44:00.60\00:44:02.57
and they know... they're
telling you, "We're tired. "
00:44:02.60\00:44:08.44
Well, the REM line
there... there is this ability
00:44:08.48\00:44:14.22
that's sort of... I want to
call it a wakefulness drive,
00:44:14.25\00:44:17.25
Cortisol and all the
things contributed to it...
00:44:17.29\00:44:19.72
it's... kind of starts
off low in the morning,
00:44:19.75\00:44:22.12
gets stronger and stronger
by the middle of the afternoon
00:44:22.16\00:44:24.53
and then it fades away.
00:44:24.56\00:44:25.89
Melatonin is what's going to
trigger that change right there
00:44:25.93\00:44:30.63
but Caffeine is
going to alter that.
00:44:30.67\00:44:34.27
If you look at
Adenosine and Caffeine,
00:44:34.30\00:44:37.84
you'll see here these...
in the center of it here,
00:44:37.87\00:44:42.24
this part right here looks very,
very similar to this part here
00:44:42.28\00:44:47.88
and indeed,
Caffeine and Adenosine
00:44:47.92\00:44:52.35
can both fit into the
same little Receptor there
00:44:52.39\00:44:56.99
but it's like a key that fits in
00:44:57.03\00:44:59.83
but it doesn't quite have
all the right notches on it
00:44:59.86\00:45:03.33
so, it fits in the keyhole
but you can't turn the lock
00:45:03.37\00:45:06.84
and that's what's
here... so Adenosine...
00:45:06.87\00:45:09.54
so, Caffeine pushes
Adenosine out of the way...
00:45:09.60\00:45:13.01
it gets in there...
00:45:13.04\00:45:14.51
but it doesn't
tell you you're tired...
00:45:14.54\00:45:16.41
now, suddenly,
I'm feeling awake...
00:45:16.44\00:45:18.25
and so, because of that now...
00:45:18.31\00:45:24.55
that's where we get
the lift from Caffeine...
00:45:24.59\00:45:27.36
it's displacing Adenosine.
00:45:27.39\00:45:29.19
Here's a very
fascinating picture right here.
00:45:29.22\00:45:32.33
The top picture
is a normal brain
00:45:32.36\00:45:36.67
with all of the
Adenosine in there.
00:45:36.70\00:45:40.94
You need Adenosine to sleep
00:45:40.97\00:45:44.74
but if you go in
and... with Caffeine...
00:45:44.77\00:45:48.94
particularly
Caffeine in the afternoon...
00:45:48.98\00:45:53.08
although there's even a
residual from morning coffee
00:45:53.11\00:45:57.89
but Caffeine later in the day
00:45:57.92\00:46:00.02
and especially
Caffeine in the evening,
00:46:00.06\00:46:03.12
is going to really
displace all of that Adenosine
00:46:03.16\00:46:06.39
so, you're going to
feel awake... alert...
00:46:06.43\00:46:08.03
and you can just keep going
but now it's time to go to sleep
00:46:08.06\00:46:11.67
and you want to go to sleep
and what happens to your sleep?
00:46:11.70\00:46:15.27
You see the
difference in the activity...
00:46:15.30\00:46:17.87
all that bright
yellow is actually...
00:46:17.94\00:46:20.44
because remember sleep is
a reactive state of the brain
00:46:20.48\00:46:23.61
and here this very
active state of the brain...
00:46:23.65\00:46:27.45
you can see it there
with all of the Adenosine
00:46:27.48\00:46:31.25
and so it's going all
that normal sleep activity,
00:46:31.29\00:46:33.86
it's going in the
deep... the Delta-wave sleep,
00:46:33.89\00:46:36.42
it's doing the deep cleaning,
00:46:36.46\00:46:37.79
it's storing stuff...
00:46:37.83\00:46:39.16
it's deleting your flash drive,
00:46:39.19\00:46:40.53
it's getting everything
ready for the next day
00:46:40.56\00:46:42.50
but with Caffeine, we've
displaced all that Adenosine
00:46:42.56\00:46:46.53
so the cells aren't going
on and doing the sleep activity
00:46:46.57\00:46:50.41
that they... they need.
00:46:50.44\00:46:51.77
Remember, that's
the normal picture.
00:46:51.81\00:46:57.01
Here is the sleep
cycle on Caffeine.
00:46:57.05\00:47:02.42
Notice, we're barely
even touching the Stage 3
00:47:02.48\00:47:06.45
not into Stage 4 at
all, just briefly there
00:47:06.52\00:47:10.43
so, those nice deep
cleaning cycles... they're gone
00:47:10.49\00:47:14.66
and look at all of the brief
awakenings here all night long
00:47:14.73\00:47:18.43
and it keeps going... look
what happened to the REM sleep,
00:47:18.50\00:47:22.20
we barely got a
few specks of REM sleep
00:47:22.24\00:47:24.47
through the entire night here
00:47:24.51\00:47:25.94
and again,
bouncing around here, so...
00:47:25.97\00:47:28.98
now, you may not feel
these brief awakenings,
00:47:29.01\00:47:31.88
you might think,
"Well, I was asleep"
00:47:31.91\00:47:33.38
but your brain was.
00:47:33.42\00:47:35.08
I mean, this brain right here
00:47:35.12\00:47:37.15
is not doing what this
brain was doing back here.
00:47:37.19\00:47:41.92
This is what you want your
sleep cycle to look like...
00:47:41.96\00:47:45.69
this is your
sleep cycle on Caffeine.
00:47:45.73\00:47:48.16
You're not getting the same
preparation for the next day,
00:47:48.20\00:47:53.03
you're not
storing the same material,
00:47:53.07\00:47:55.10
you're not cleaning
out your flash drive,
00:47:55.14\00:47:57.14
you're not doing
the deep cleaning
00:47:57.21\00:47:58.87
and, of course, this
is a real simplification,
00:47:58.91\00:48:01.61
there's a lot of complex
things that are still happening
00:48:01.64\00:48:03.95
and we're still
learning more about it
00:48:03.98\00:48:05.31
but you can see that
Caffeine is a real detriment
00:48:05.35\00:48:10.85
to a normal sleep cycle.
00:48:10.89\00:48:13.25
If you want to have a brain
00:48:13.29\00:48:15.62
that's actually
going to function right
00:48:15.66\00:48:17.29
and do everything right,
00:48:17.33\00:48:18.69
you're going to need to
get rid of the Caffeine,
00:48:18.73\00:48:23.20
you know, we've been
advised for many decades now
00:48:23.23\00:48:27.64
that Caffeine is something
that needs to be eliminated
00:48:27.67\00:48:30.61
and removed from
our diets entirely.
00:48:30.64\00:48:34.71
You know, it's one of the things
that you're going to have to do
00:48:34.74\00:48:38.91
if you want to have a
normal, good sleep cycle...
00:48:38.95\00:48:42.95
if you want to
have normal neurons,
00:48:42.98\00:48:44.72
if we have a normal functioning
cortex... frontal lobes...
00:48:44.75\00:48:50.13
all of that depends
on a good night's sleep
00:48:50.16\00:48:52.13
and good night's sleep
depends on being Caffeine free.
00:48:52.16\00:48:56.53
Just remember the difference
00:48:56.56\00:48:58.33
between those
two pictures there.
00:48:58.37\00:48:59.90
Pause...
00:48:59.93\00:49:02.10
What about sleeping
pills to help you sleep?
00:49:02.14\00:49:04.44
Do they overcome Caffeine?
00:49:04.47\00:49:06.04
No, sleeping
pills... is sort of like
00:49:06.07\00:49:10.95
a mild version of
General Anesthesia.
00:49:10.98\00:49:15.82
Now, when you go
into the operating room
00:49:15.85\00:49:19.29
and they give you
an Anesthetic agent
00:49:19.32\00:49:22.69
to make you unconscious
so you don't feel pain,
00:49:22.72\00:49:26.03
you don't feel the surgery
00:49:26.06\00:49:28.23
and the surgeon can go
ahead and operate easily
00:49:28.26\00:49:31.70
and finish the surgery
without you being in pain
00:49:31.73\00:49:35.14
or thrashing
around... anything...
00:49:35.17\00:49:36.87
your brain is just turned off.
00:49:36.91\00:49:40.08
Remember, sleep is
a very active state...
00:49:40.11\00:49:43.58
there's a lot of
things happening,
00:49:43.65\00:49:44.98
Anesthetics go to the
Neurons and anesthetize them,
00:49:45.01\00:49:50.99
they put them out,
they just knock them out,
00:49:51.02\00:49:53.19
they stop working there
00:49:53.22\00:49:55.26
and in this knock-out
state, they're not sleeping,
00:49:55.29\00:49:58.59
they're not doing
anything, you're not conscious,
00:49:58.63\00:50:01.90
you're asleep...
00:50:01.96\00:50:03.30
but that's what the
sleeping pills are doing.
00:50:03.33\00:50:06.80
So, you're not awake but
you're still deprived of sleep,
00:50:06.84\00:50:12.71
you're not actually
getting the sleep because
00:50:12.74\00:50:16.31
the sleeping pills are
just anesthetizing you.
00:50:16.34\00:50:19.91
Pause...
00:50:19.95\00:50:23.99
What about alcohol?
00:50:24.02\00:50:25.39
A lot of people think
that a glass of wine at bedtime
00:50:25.45\00:50:30.89
is an ideal way...
nightcap... that gets you ready
00:50:30.93\00:50:36.36
and helps you fall asleep
00:50:36.40\00:50:37.73
and it's just the
way to end the day...
00:50:37.77\00:50:40.57
calm everything down
and put you to sleep.
00:50:40.60\00:50:43.51
What does
alcohol do to the brain?
00:50:43.57\00:50:45.97
Alcohol is going to just...
00:50:46.01\00:50:48.71
it's going to put it out.
00:50:48.74\00:50:51.41
It's like the sleeping pill.
00:50:51.45\00:50:54.02
Alcohol shuts down the
brain depriving you of sleep
00:50:54.05\00:51:00.79
particularly REM sleep.
00:51:00.86\00:51:03.59
With alcohol... an alcoholic is
very, very deprived of REM sleep
00:51:03.63\00:51:11.13
because it knocks out REM sleep
00:51:11.17\00:51:13.94
even more than some of
the other phases of sleep.
00:51:13.97\00:51:16.71
There's almost no REM
sleep at all in an alcoholic.
00:51:16.74\00:51:20.98
In the Emergency Room
we sometimes get alcoholics
00:51:21.04\00:51:25.21
in various kinds of crisis...
00:51:25.28\00:51:26.85
what we call: Acute
Alcohol withdrawal...
00:51:26.88\00:51:29.65
it can go into
various DTs and stuff
00:51:29.68\00:51:32.32
and one of the aspects
of acute alcohol withdrawal
00:51:32.35\00:51:36.49
is hallucinations.
00:51:36.52\00:51:39.53
Hallucinations...
it's like your REM sleep...
00:51:39.56\00:51:44.83
all of these various,
you know, bizarre images
00:51:44.87\00:51:50.11
and thoughts and
things coming together
00:51:50.14\00:51:52.57
and colliding in various ways
00:51:52.64\00:51:54.18
and during the
alcohol withdrawal,
00:51:54.21\00:51:58.91
the brain which has been
so deprived of REM sleep...
00:51:58.95\00:52:01.88
now the alcohol is off...
00:52:01.92\00:52:03.39
the alcohol is all worn off
00:52:03.42\00:52:04.85
and now they're in
this withdrawal state
00:52:04.89\00:52:06.76
and there's like the brain says,
00:52:06.79\00:52:08.39
"We're going to
catch up on REM sleep"
00:52:08.42\00:52:10.03
and it starts going into REM
sleep while they're still awake
00:52:10.06\00:52:14.33
and they're seeing
people that aren't there
00:52:14.36\00:52:17.00
and snakes crawling up the wall
00:52:17.03\00:52:18.67
and spiders
crawling across their bed
00:52:18.70\00:52:21.04
and all kinds of stuff like that
00:52:21.07\00:52:23.04
and it's very dysphoric type
of REM that's coming back there
00:52:23.07\00:52:29.14
while they're awake
in these hallucinations
00:52:29.21\00:52:31.18
and we usually give people
sedatives to put the brain out
00:52:31.21\00:52:36.08
because these are so harmful.
00:52:36.15\00:52:37.85
Of course, with the alcohol
withdrawal, they go to seizures
00:52:37.89\00:52:40.29
and a lot of other things
00:52:40.32\00:52:41.66
so we want to
usually knock that down
00:52:41.69\00:52:43.63
and prevent that
00:52:43.66\00:52:44.99
but alcohol is really
00:52:45.03\00:52:48.33
not the choice if you
want a good night's sleep.
00:52:48.36\00:52:52.43
I know it's not the
popular culture right now
00:52:52.47\00:52:56.47
but the reality is:
Alcohol will not give you
00:52:56.50\00:53:00.48
the sleep you need.
00:53:00.51\00:53:01.84
What are the things that can
help you get the sleep you need?
00:53:01.88\00:53:05.35
Adequate
exercise during the day.
00:53:05.38\00:53:08.28
Many of us go to bed...
we're exhausted mentally
00:53:08.32\00:53:12.19
but we physically
haven't had the exercise.
00:53:12.22\00:53:15.02
You need a good
workout at the gym
00:53:15.06\00:53:16.99
or if you've got a physical job,
00:53:17.03\00:53:18.66
you've got a
real blessing there.
00:53:18.69\00:53:20.26
Physical exercise of an
adequate amount during the day
00:53:20.30\00:53:24.63
when you come up to bedtime,
00:53:24.67\00:53:26.43
the muscles and the other parts
of the body are tired enough
00:53:26.47\00:53:30.04
that they're going to say,
00:53:30.07\00:53:31.41
"Okay, we're ready
to shift into sleep... "
00:53:31.44\00:53:34.71
and the brain and
synchrony with that says,
00:53:34.74\00:53:38.31
"Yeah, let's go
to sleep now... "
00:53:38.35\00:53:39.68
and the various
parts all come together
00:53:39.71\00:53:42.05
if you really good sound sleep,
if you've had enough exercise.
00:53:42.08\00:53:45.69
Going to bed on an
empty stomach is important.
00:53:45.72\00:53:49.22
If you're just
going to have a large meal
00:53:49.26\00:53:53.06
and you haven't
digested that meal yet,
00:53:53.09\00:53:56.80
well, the brain is
sending all these messages down
00:53:56.87\00:53:59.80
through various ganglions
00:53:59.83\00:54:01.17
and now, we've got to
work on the stomach...
00:54:01.20\00:54:04.11
put out the digestive...
00:54:04.14\00:54:05.47
you're doing all
of this work down here
00:54:05.51\00:54:07.51
and it's like,
"Hey, the brain doesn't...
00:54:07.54\00:54:09.64
the brain
controls all of that. "
00:54:09.68\00:54:11.01
You know, you don't know...
00:54:11.05\00:54:12.38
decide when to contract your
stomach, the brain decides that.
00:54:12.41\00:54:14.85
You don't decide when to
move it down the intestines,
00:54:14.88\00:54:17.52
you don't decide
when to go into the colon,
00:54:17.55\00:54:19.45
you know, you don't
decide all these things,
00:54:19.49\00:54:21.32
they're all done
automatically by your brain
00:54:21.36\00:54:23.12
but right now, we want the
brain to go in a sleep cycle.
00:54:23.16\00:54:28.36
Well, the sleep cycle
is going to be mixed up
00:54:28.40\00:54:30.90
because the stomach's
telling, "Hey, we've got...
00:54:30.97\00:54:33.37
there's lot of food, we've got
to do something about it here
00:54:33.40\00:54:35.10
and it's sending messages up
00:54:35.14\00:54:36.47
and so, there's this
conflict of the digestive system
00:54:36.50\00:54:39.57
telling the brain,
"Hey, we can't go to sleep,
00:54:39.61\00:54:40.98
we've got to keep... you've
got to keep processing this... "
00:54:41.01\00:54:43.18
and the brain says, "Okay,
well, let's send this up there"
00:54:43.21\00:54:45.35
the sleep cycle down there
00:54:45.38\00:54:48.22
is not, you know,
going to be as good
00:54:48.28\00:54:50.39
in that condition there.
00:54:50.42\00:54:51.92
Cool, dark, lack of things
working into it to interrupt it.
00:54:51.95\00:55:00.10
If you'd like to
read some more about this,
00:55:00.13\00:55:04.37
there's an excellent book...
came out about a year ago,
00:55:04.40\00:55:08.00
"Why We Sleep"
00:55:08.04\00:55:09.44
Matthew Walker is a PhD who
specializes in sleep studies.
00:55:09.47\00:55:13.41
He is one of the
Scientists that has discovered
00:55:13.48\00:55:16.91
much of the recent information
about what's happening
00:55:16.95\00:55:20.48
during the time we sleep
00:55:20.52\00:55:21.85
I've been
through a lot of his work
00:55:21.88\00:55:23.79
but he's put together
a very readable book here
00:55:23.82\00:55:26.15
that was really... yeah...
00:55:26.19\00:55:28.19
if you're interested
to know more about sleep,
00:55:28.22\00:55:30.06
I would highly recommend that as
a... something valuable there.
00:55:30.09\00:55:35.13
Pause...
00:55:35.16\00:55:39.40
A final thought here,
00:55:39.43\00:55:42.60
delicate nerves of the brain
00:55:42.64\00:55:44.27
are the only channel through
which God communicates with man.
00:55:44.31\00:55:49.18
You think about
that for a minute...
00:55:49.21\00:55:53.11
we want all those
neurons in the brain
00:55:53.15\00:55:56.99
to be doing exactly
what God designed them to do
00:55:57.02\00:56:02.52
and one of those things is going
to be able to commune with God
00:56:02.56\00:56:07.33
and you need the frontal lobe...
all of the other lobes...
00:56:07.36\00:56:12.33
all of these parts synapsing.
00:56:12.37\00:56:14.60
You need the neurons clean
00:56:14.64\00:56:16.81
so they can
respond appropriately.
00:56:16.84\00:56:18.61
Everything about sleep
00:56:18.64\00:56:21.08
is essential for a
normal functioning brain.
00:56:21.11\00:56:24.28
The sleep-deprived brain is
going to make it more difficult.
00:56:24.31\00:56:28.42
A Caffeinated brain is going
to find it really difficult.
00:56:28.45\00:56:32.52
An alcohol brain
that's intoxicated...
00:56:32.55\00:56:36.26
a brain with various
mind-altering drugs, you know,
00:56:36.29\00:56:40.36
sleeping pill... all of
these things that come on there,
00:56:40.40\00:56:43.47
they alter the functioning
of the neurons in the brain
00:56:43.50\00:56:46.50
are disturbing that
delicate balance in there.
00:56:46.53\00:56:50.44
Remember, there's different
little neurotransmitters
00:56:50.47\00:56:52.57
all over the place connecting
all of the parts of the brain.
00:56:52.61\00:56:55.24
We want our brains to be
as clear and finely tuned
00:56:55.28\00:56:59.95
and as ready as they
can be to be sensitive
00:56:59.98\00:57:04.25
to the voice of
God speaking to us.
00:57:04.29\00:57:06.79
We want to have a clear
mind to pray... to think...
00:57:06.82\00:57:12.99
to put our thoughts together.
00:57:13.03\00:57:14.60
Well, we need to have
stored the important stuff,
00:57:14.63\00:57:18.27
cleaned out the
unimportant stuff.
00:57:18.30\00:57:19.97
We want the creative
parts of the mind working well
00:57:20.00\00:57:22.47
and now, God's got a temple
that He can come and dwell in.
00:57:22.50\00:57:27.34
Pause...
00:57:27.38\00:57:30.08
The door to the
tabernacle is inside you.
00:57:30.15\00:57:32.81
God's placed it there...
that's the temple He dwells in,
00:57:32.85\00:57:37.29
it's in this brain with
these neurons and sleep.
00:57:37.32\00:57:41.22
My prayer is that you will
have sleep... a sound sleep
00:57:41.26\00:57:44.66
and a clear mind
00:57:44.69\00:57:46.03
and God will bless you
by communicating with you.
00:57:46.06\00:57:49.63