Welcome back we've been talking with Dr. Neil Nedley 00:00:01.98\00:00:03.40 and we've talked about some exciting things 00:00:03.41\00:00:05.60 we're glad you're with us Dr. Neil Nedley. 00:00:05.61\00:00:06.96 Well, thank you it's good to be here Don, as always. 00:00:06.97\00:00:10.11 Now let's continue our discussion 00:00:10.12\00:00:11.99 we have some other studies to look at, 00:00:12.00\00:00:13.41 we want to look at sports and the placebo effect. 00:00:13.42\00:00:16.18 Yes, it's kind of interesting 00:00:17.03\00:00:18.40 we've looked at placebo effect as far as diseases concerned 00:00:18.41\00:00:21.96 and that's why we do what's called randomized studies 00:00:21.97\00:00:25.64 where if we really want to see of something 00:00:25.65\00:00:27.42 it's beneficial like we've just looked at 00:00:27.43\00:00:30.27 red yeast rice for instance, 00:00:30.28\00:00:32.21 we take it and compare with a placebo 00:00:32.22\00:00:34.37 and then do a comparison study and the individual doesn't know 00:00:34.38\00:00:38.21 if they're getting the active component 00:00:38.22\00:00:40.34 or the placebo in that way 00:00:40.35\00:00:42.70 we can see is a due to their 00:00:42.71\00:00:44.28 believe the things got better 00:00:44.29\00:00:46.52 or is it actually due to something beneficial 00:00:46.53\00:00:48.95 in the product. Okay. 00:00:48.96\00:00:50.31 And in that case the American Journal Cardiology reported 00:00:50.32\00:00:53.12 that red yeast rice extract was indeed very beneficial. 00:00:53.13\00:00:59.13 Again as compare to placebo. 00:00:59.14\00:01:00.95 But we haven't really done placebo studies 00:01:00.96\00:01:03.25 as far as sports enhancement is concerned. 00:01:03.26\00:01:06.39 So this is like whether not sports, 00:01:06.40\00:01:08.34 sports enhance your physical well being. 00:01:08.35\00:01:11.89 Well, you know this is like taking products 00:01:11.90\00:01:13.61 for sports enhancement you know. Okay. 00:01:13.62\00:01:15.41 For instance the weight lifters 00:01:15.42\00:01:16.43 have a tendency to wanna steroids 00:01:16.44\00:01:18.61 or... Okay, absolutely. 00:01:18.62\00:01:19.59 They want to take growth hormones. 00:01:19.60\00:01:20.62 In fact, this study that you're seeing 00:01:20.63\00:01:22.37 the graphic upon the screen 00:01:22.38\00:01:24.20 shows the Athletic Boost from Growth Hormones 00:01:24.21\00:01:28.02 actually is not due to the growth hormone. 00:01:28.03\00:01:30.35 It's mental. It's mental, in other words 00:01:30.36\00:01:33.22 it's to belief that the growth hormone is going, 00:01:33.23\00:01:35.60 is going to help that actually built those muscles up 00:01:35.61\00:01:39.45 to a stronger component. 00:01:39.46\00:01:41.83 And they did the study that showed this. 00:01:41.84\00:01:43.92 Yes, they did a study 00:01:43.93\00:01:45.28 by injecting either growth hormone into the individual 00:01:45.29\00:01:48.33 or growth or actually a placebo 00:01:48.34\00:01:50.72 where the individual thought 00:01:50.73\00:01:52.32 they were getting growth hormone. 00:01:52.33\00:01:53.78 And then they compared the two groups 00:01:53.79\00:01:55.87 and what they found out is everyone in the study 00:01:55.88\00:01:58.84 whether they were in a placebo arm 00:01:58.85\00:02:00.86 or the growth hormone arm 00:02:00.87\00:02:02.11 improved about one to two percent 00:02:02.12\00:02:04.24 as far as muscle performances concerned 00:02:04.25\00:02:07.86 and Athletic performance, 00:02:07.87\00:02:09.19 but if you are in the placebo group, 00:02:09.20\00:02:11.36 in other words, you wrongly thought 00:02:11.37\00:02:13.84 that you had received growth hormone 00:02:13.85\00:02:15.84 your performance enhancement was twice that 3 to 5% 00:02:15.85\00:02:20.91 and the phenomena was far greater 00:02:20.92\00:02:22.90 in men than in women often we say that women 00:02:22.91\00:02:26.50 are more pronto placebo effect and the mental belief aspect 00:02:26.51\00:02:30.26 but as far as athletic performances concerned 00:02:30.27\00:02:32.67 men are actually more pronto to it. 00:02:32.68\00:02:34.69 So what do you make of these kind of studies 00:02:34.70\00:02:36.74 because what you're basically saying is, 00:02:36.75\00:02:38.43 you know, these things are really help you 00:02:38.44\00:02:40.80 that's what you're saying, 00:02:40.81\00:02:41.78 but what do you replace it if they thank it's helping them 00:02:41.79\00:02:46.11 and it's not the thinking that was helping them 00:02:46.12\00:02:49.33 is what health plan and if you take that away 00:02:49.34\00:02:51.88 then they're not gonna get help this much, so what do you do? 00:02:51.89\00:02:54.29 Well, I think the point of the study is 00:02:54.30\00:02:57.40 that the mind plays amazing tricks on the body. 00:02:57.41\00:03:00.45 And the placebo effect has been known for centuries, 00:03:00.46\00:03:03.82 but it also you know, that the take home message 00:03:03.83\00:03:06.49 and that says just because someone makes a claim 00:03:06.50\00:03:09.28 that a product helped them doesn't necessarily mean 00:03:09.29\00:03:13.07 that their product really helped them. 00:03:13.08\00:03:14.66 And last they really enrolled in a study 00:03:14.67\00:03:16.88 and that's the importance of scientific studies 00:03:16.89\00:03:19.74 where we can involve groups of people 00:03:19.75\00:03:22.12 and actually do comparison 00:03:22.13\00:03:23.71 and it turns out for those of you 00:03:23.72\00:03:25.21 that are in sport don't take growth hormone 00:03:25.22\00:03:27.42 actually just belief that what you're doing is helping 00:03:27.43\00:03:31.12 and you'll do better than growth hormone. 00:03:31.13\00:03:32.91 So that's it, that's the answer 00:03:32.92\00:03:34.36 just belief on the basis of what you've said 00:03:34.37\00:03:37.34 and instead taking the stuff 00:03:37.35\00:03:39.17 that really could be quite damaging. 00:03:39.18\00:03:40.69 Correct. Okay. Correct. 00:03:40.70\00:03:42.59 All right, well let's go to the next one 00:03:42.60\00:03:44.38 I think it's fascinating as well 00:03:44.39\00:03:45.91 and it had to do with the relationship 00:03:45.92\00:03:47.97 between exercises increase protein, 00:03:47.98\00:03:51.51 what was this study about? 00:03:51.52\00:03:53.05 Well, it show that exercise increases 00:03:53.06\00:03:56.74 in important protein called BDNF. 00:03:56.75\00:04:01.24 And in fact, that right there on the screen 00:04:02.44\00:04:04.16 that you can see Exercise Increases that Protein 00:04:04.17\00:04:07.91 and the importance of BDNF 00:04:07.92\00:04:10.38 actually is not only that it helps the brain 00:04:10.39\00:04:13.99 in fact, the term for BDNF 00:04:14.88\00:04:19.24 is Brain-derived neurotrophic factor. 00:04:19.25\00:04:22.95 Brain-derived neurotrophic factor, 00:04:22.96\00:04:26.13 which means I can understand the brain and it's derived 00:04:26.14\00:04:29.93 from a... from a neurotrophic factor. 00:04:29.94\00:04:34.32 Well, neurotrophic means 00:04:34.33\00:04:35.68 it actually supplies the neurons with nutrition. 00:04:35.69\00:04:39.62 That they need. Exactly, 00:04:39.63\00:04:41.29 it's a factor that helps the neurons to work better. 00:04:41.30\00:04:44.07 So in other words, if you exercise the B 00:04:44.08\00:04:46.50 this particular BDNF goes up 00:04:46.51\00:04:49.84 and lessens the appetite. That's right. 00:04:49.85\00:04:53.85 And so lot of people think well exercise is only 00:04:53.86\00:04:57.25 you know taking away maybe if you for instance, 00:04:57.26\00:05:00.05 if you do brisk walking for an hour a day 00:05:00.06\00:05:02.78 which is quite a bit of brisk walking 00:05:02.79\00:05:04.04 you've only lost about 500 calories by doing that. 00:05:04.05\00:05:07.12 And so people say, well you know, 00:05:07.13\00:05:08.98 exercise may not be all that important in weight loss 00:05:08.99\00:05:11.42 it's a whole lot easier 00:05:11.43\00:05:12.70 to not eat those two slices of American cheese 00:05:12.71\00:05:16.50 that are worth to 500 calories 00:05:16.51\00:05:18.81 then they go out and walk for an hour 00:05:18.82\00:05:20.55 and so the secret is to really cut down on what you're eating, 00:05:20.56\00:05:25.13 but this shows that when we do exercise in proper ways 00:05:25.14\00:05:29.62 we actually secrete a chemical that helps us not to over-eat. 00:05:29.63\00:05:34.21 Interesting, can we just get that 00:05:34.22\00:05:36.08 chemical without having to exercise, 00:05:36.09\00:05:37.62 can we get it off the shelf just like everything else? 00:05:37.63\00:05:39.78 Well, not necessarily 00:05:39.79\00:05:42.90 exercise is a good way of doing it, 00:05:42.91\00:05:45.37 but also weight loss in and of itself can do this 00:05:45.38\00:05:48.69 you know intermittent fasting, 00:05:48.70\00:05:50.05 okay, can increase BDNF. 00:05:50.06\00:05:52.67 But there is no way to get this particular hormone. 00:05:52.68\00:05:56.08 No there is, it's not in the bottle 00:05:56.09\00:05:57.40 it's not in a supplement. 00:05:57.41\00:05:58.47 Yeah, that's only made by the brain. Okay. 00:05:58.48\00:06:00.65 And so at this point in time we haven't found out, 00:06:00.66\00:06:02.95 in fact it's really hard to get proteins 00:06:02.96\00:06:04.71 like that into the brain 00:06:04.72\00:06:06.05 even if you word a consumer in a bottle 00:06:06.06\00:06:08.63 because it won't cross the blood brain barrier, 00:06:08.64\00:06:10.63 these proteins have to be made inside the brain. 00:06:10.64\00:06:12.84 I see. And never any affected, okay. 00:06:12.85\00:06:15.30 So this study if I want to read more about it, 00:06:15.31\00:06:17.37 where do we get the studies from? 00:06:17.38\00:06:18.71 Well, this particular study 00:06:18.72\00:06:21.92 was done by Dr. Henry Anhalt of the Animas Corporation. 00:06:21.93\00:06:27.31 He is from West Chester, Pennsylvania. 00:06:27.32\00:06:29.26 And actually wasn't publish 00:06:29.27\00:06:31.09 it was presented at the Endocrine Society's 00:06:31.10\00:06:33.75 2008 meeting in San Francisco 00:06:33.76\00:06:36.91 it probably well republished forth coming. 00:06:36.92\00:06:39.58 fascinating, so get out their exercise 00:06:39.59\00:06:42.69 secrete the hormone you need. Yes. 00:06:42.70\00:06:45.28 And this will not only help you loose those calories, 00:06:45.29\00:06:48.52 but keep helping you not be you know given to over eating. 00:06:48.53\00:06:53.67 That's right, exactly. 00:06:53.68\00:06:55.39 Physical exercise and recovery of cancer patients. 00:06:56.31\00:07:00.22 Yes, a lot of people just have this assumption that you know, 00:07:00.23\00:07:03.79 I'm diagnosed with this deadly cancer. 00:07:03.80\00:07:05.94 And I just need to take life easy 00:07:05.95\00:07:08.53 you know I shouldn't be stressed, exercise is stressful 00:07:08.54\00:07:11.54 and you know I just need to get the treatment radiation 00:07:11.55\00:07:16.31 like chemo whatever treatment I'm and kind of take life easy. 00:07:16.32\00:07:19.66 It turns out those individuals don't do near as well 00:07:19.67\00:07:22.91 as those who actually start a physical training program 00:07:22.92\00:07:27.00 even in the midst of their chemo and radiation 00:07:27.01\00:07:29.56 they start a physical training program 00:07:29.57\00:07:32.53 as part of what we called Cancer Rehabilitation. 00:07:32.54\00:07:36.07 So even though you're down you have those treatments 00:07:37.07\00:07:39.45 or whatever you're going through get out there 00:07:39.46\00:07:41.18 and still exercise regardless 00:07:41.19\00:07:43.08 of how you feel it's gonna help you. 00:07:43.09\00:07:44.64 These people showed significant improvements 00:07:45.57\00:07:47.24 in physical function. 00:07:47.25\00:07:48.56 These physical improvements lasted for even three months 00:07:49.53\00:07:52.45 after the training program was over with compared 00:07:52.46\00:07:54.86 with those at least three months, 00:07:54.87\00:07:56.26 they only did the study three months afterwards. 00:07:56.27\00:07:58.50 And they also found out that they did better emotionally, 00:07:58.51\00:08:03.11 they did better physically 00:08:03.12\00:08:05.11 and exercise is a very important component 00:08:05.12\00:08:08.52 actually pushing it 00:08:08.53\00:08:09.65 and even getting involved in group activities 00:08:09.66\00:08:12.94 social types of exercise seem to benefit 00:08:12.95\00:08:16.11 these cancer patient as well not just the individual exercise. 00:08:16.12\00:08:19.39 And that study is from where if we want to read more about it. 00:08:19.40\00:08:22.01 That study was published in Psychosomatic Medicine 00:08:22.02\00:08:24.91 in May of 2008. Fascinating okay, 00:08:24.92\00:08:28.27 one last study before we finish today's program 00:08:28.28\00:08:31.99 and that is too much sleep increases stroke risk. 00:08:32.00\00:08:35.59 Too much sleep, 00:08:35.60\00:08:37.13 yeah a lot of times we talked about too little sleep. 00:08:37.14\00:08:39.57 But this study show that regularly getting nine hours 00:08:39.58\00:08:43.35 or more of sleep per night increases the risk of stroke 00:08:43.36\00:08:46.50 in postmenopausal women. 00:08:46.51\00:08:48.43 So now it was after the change. 00:08:48.44\00:08:49.97 After the change. 00:08:49.98\00:08:50.97 It's okay to sleep a lot before the change. 00:08:50.98\00:08:53.04 Well, now studies have actually shown in other ways 00:08:53.05\00:08:57.03 too much sleep is harmful 00:08:57.04\00:08:58.46 can actually lead to depression for instance. 00:08:58.47\00:09:00.80 But only 5% of women age is 50 to 79 00:09:00.81\00:09:04.26 are getting too much sleep. 00:09:04.27\00:09:05.46 And so it's not a large group but the study showed 00:09:06.75\00:09:11.01 that they had a 60 to 70% higher risk of stroke 00:09:11.02\00:09:15.63 that significant. That's huge. 00:09:15.64\00:09:17.55 Even those who get too little sleep 00:09:17.56\00:09:19.17 only have a 14% increase risk of stroke. 00:09:19.18\00:09:21.91 So we know too little sleep is bad, 00:09:21.92\00:09:24.07 but that increases the risk of stroke slightly 00:09:24.08\00:09:26.29 if you get too much sleep 00:09:26.30\00:09:27.84 it increases the risk of stroke pretty dramatically. 00:09:27.85\00:09:31.08 Tell us with that studies from then I have a question for you. 00:09:31.91\00:09:34.03 Well, the study was actually presented 00:09:34.04\00:09:37.21 by Sylvia Webster high, smaller 00:09:37.22\00:09:40.11 of Albert Einstein College of Medicine in New York 00:09:40.12\00:09:43.80 and it was presented 00:09:43.81\00:09:44.89 at the American Heart Association journal Stroke 00:09:44.90\00:09:48.10 in this would have been July of 2008. 00:09:48.11\00:09:51.92 So what's too little sleep, what's too much sleep, 00:09:51.93\00:09:55.10 how many hours is the right amount of sleep? 00:09:55.11\00:09:57.32 Too much is greater than nine, 00:09:57.33\00:09:59.34 too little is greater than six. Great. 00:09:59.35\00:10:02.57 I'm sorry less than six. 00:10:02.58\00:10:03.96 Yeah, less than six greater than nine 00:10:03.97\00:10:06.27 and most people need about seven to eight 00:10:06.28\00:10:08.58 that seems the eight hours 00:10:08.59\00:10:10.49 point seems to be pretty idea for most individuals. 00:10:10.50\00:10:13.49 And to get that readjusted if you're off, 00:10:13.50\00:10:16.22 what's the best way to get a readjusted? 00:10:16.23\00:10:18.26 Light therapy actually, believe it or not 00:10:19.27\00:10:21.83 and if you get light therapy in the morning 00:10:21.84\00:10:23.86 it set your body clock you're tired in the evening 00:10:23.87\00:10:27.08 and you're able to go to sleep much better. 00:10:27.09\00:10:29.07 So open up those drapes 00:10:29.08\00:10:30.36 and turn to those bed lights on and then reset your clock. 00:10:30.37\00:10:33.03 In the morning, that's right. 00:10:33.04\00:10:34.45 And then even a mid-afternoon exposure can be helpful. 00:10:34.46\00:10:37.67 Well, Dr. Nedley you've updated to some a lot of different areas 00:10:37.68\00:10:40.93 and then very useful information no matter 00:10:40.94\00:10:44.00 you know, if you're someone was taking maybe 00:10:44.01\00:10:46.58 growth hormone to get stronger or anything else. 00:10:46.59\00:10:49.13 We're glad that you've been with us today, 00:10:49.14\00:10:50.73 thanks for being with us. 00:10:50.74\00:10:51.71 Thank you very much, Don. 00:10:51.72\00:10:52.87 And thank you for being with us today, 00:10:52.88\00:10:54.24 we hope that you know, you'll take these things 00:10:54.25\00:10:57.32 to heart anything from red yeast extract, 00:10:57.33\00:11:02.15 a very positive substance 00:11:02.16\00:11:04.23 or and any of these other just great tips you've heard today 00:11:04.24\00:11:06.95 and as a result of this program 00:11:06.96\00:11:09.04 you have health at last not just for now, but for a lifetime. 00:11:09.05\00:11:14.32